Compile Data Set for Download or QSAR
Found 164 with Last Name = 'fujiwara' and Initial = 's'
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115243((S)-N-[7-(5-fluoro-2-methylphenyl)-4-methyl-(7S)-5...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115239((S)-N-[7-(2,5-dichloro-3-thienyl)-4-methyl-(7S)-5,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115246(CHEMBL543867 | N-[7-(2-chloro-5-fluorophenyl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115271(CHEMBL556009 | N-[7-(2,5-dichloro-3-thienyl)-4-met...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115248(CHEMBL552723 | N-[7-(3-chloro-2-thienyl)-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115267(CHEMBL102546 | N-[7-(2-chlorophenyl)-4-methyl-(7S)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115335(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115302(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Platelet-derived growth factor receptor betaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115351(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115268(CHEMBL554001 | N-[7-(2-chloro-3-thienyl)-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115238(CHEMBL552865 | N-[7-(2-chlorophenyl)-4-methyl-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115347(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115245(CHEMBL554215 | N-[4-methyl-7-(3-thienyl)-5,6,7,8-t...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115233(CHEMBL541577 | N-[7-(2-fluorophenyl)-4-methyl-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115236(CHEMBL542925 | N-[7-(5-fluoro-2-methoxyphenyl)-4-m...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115270((R)-N-[7-(2,5-dichloro-3-thienyl)-4-methyl-(7R)-5,...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115264(CHEMBL552934 | N-[3-methyl-6-(2-methylphenyl)-4,5,...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115258(CHEMBL555535 | N-[7-(5-fluoro-2-methylphenyl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115257(CHEMBL542687 | N-[7-(2,5-difluorophenyl)-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115256(CHEMBL543148 | N-[7-(2-chlorophenyl)-4-methyl-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115252(CHEMBL552827 | N-[4-methyl-7-(2-thienyl)-5,6,7,8-t...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115260(CHEMBL545732 | N-[7-(3,5-dichloro-2-thienyl)-4-met...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115302(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of Flt3 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115301(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of Platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115302(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of Mast/stem cell growth factor receptor (c-Kit kinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115234(CHEMBL105412 | N-[7-(2-chlorophenyl)-4-methoxy-5,6...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115299(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115301(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of Mast/stem cell growth factor receptor (c-Kit kinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115241(CHEMBL541918 | N-[6-(2-chlorophenyl)-3-methyl-4,5,...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115259(CHEMBL554422 | N-[7-(2-bromophenyl)-4-methyl-5,6,7...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115228(CHEMBL552540 | N-[4-methyl-7-(2-methylphenyl)-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115255(CHEMBL540813 | N-[7-(2,5-dichlorophenyl)-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115331(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115229(CHEMBL553754 | N-[7-(3-chlorophenyl)-4-methyl-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115301(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115319(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115302(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115235(CHEMBL541833 | N-[6-(2-chlorophenyl)-3-methyl-4,5,...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115269(CHEMBL554686 | N-[7-(2,3-dichlorophenyl)-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115302(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of Platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115261(CHEMBL543865 | N-(4-methyl-7-phenyl-5,6,7,8-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115354(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115308(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115253(CHEMBL555103 | N-[7-(2-methoxyphenyl)-4-methyl-5,6...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115306(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115242(CHEMBL554125 | N-[7-(2-furyl)-4-methyl-5,6,7,8-tet...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115301(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Platelet-derived growth factor receptor betaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115298(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Mast/stem cell growth factor receptor (c-Kit kinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115327(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX9BDPPubMed
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