TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Platelet-derived growth factor receptor betaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Flt3 kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Mast/stem cell growth factor receptor (c-Kit kinase)More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Mast/stem cell growth factor receptor (c-Kit kinase)More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of Platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Takeda Chemical Industries, Ltd.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Platelet-derived growth factor receptor betaMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Mast/stem cell growth factor receptor (c-Kit kinase)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair