Compile Data Set for Download or QSAR
Found 559 with Last Name = 'gilbert' and Initial = 's'
TargetBreast cancer type 1 susceptibility protein(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50221433(1-(9,10,10-trioxo-9,10-dihydro-10lambda*6*-thioxan...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of BRCA1 assessed as BRCT-BACH1 interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8D7PPubMed
TargetBreast cancer type 1 susceptibility protein(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50221434(3-(4-benzyl-piperidin-1-yl)-10,10-dioxo-10H-10lamb...)copy SMILEScopy InChI
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of BRCA1 assessed as BRCT-BACH1 interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8D7PPubMed
TargetBreast cancer type 1 susceptibility protein(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50221432(3-(4-methyl-piperidin-1-yl)-10,10-dioxo-10H-10lamb...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of BRCA1 assessed as BRCT-BACH1 interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8D7PPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.631nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341249(1,1-Dimethylethyl{(3R,5R)-1-[2-Amino-6-(3-amino-1H...)copy SMILEScopy InChI
Affinity DataIC50: 0.794nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181274(5-(3-((S)-2-((R)-4-(3-chlorophenyl)-3-hydroxybutyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341241((3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341243((3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341239((3S,6R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-p...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341246((2S,5R)-4-[6-(3-amino-1H-indazol-6-yl)-2-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341245((2S,5R)-4-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50095027((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50095027((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341244((2S,5R)-4-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-p...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181298(5-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341247((2S,5R)-4-[6-(3-Amino-1H-indazol-6-yl)-2-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341248(1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341242((3S,6R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-p...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341249(1,1-Dimethylethyl{(3R,5R)-1-[2-Amino-6-(3-amino-1H...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418251(CHEMBL1614776)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418251(CHEMBL1614776)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181289(5-(3-((S)-2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341249(1,1-Dimethylethyl{(3R,5R)-1-[2-Amino-6-(3-amino-1H...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of PDK1-mediated RSK phosphorylation at Ser221 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418241(CHEMBL1614774)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418233(CHEMBL1765876)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50142488(7-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181296(5-(3-((S)-2-(3-hydroxy-4-phenylbutyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181279(7-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrr...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341246((2S,5R)-4-[6-(3-amino-1H-indazol-6-yl)-2-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetAurora kinase B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418247(CHEMBL1765745)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418233(CHEMBL1765876)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418250(CHEMBL1765748)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460885(CHEMBL4227912)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341246((2S,5R)-4-[6-(3-amino-1H-indazol-6-yl)-2-(methylam...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of PDK1-mediated RSK phosphorylation at Ser221 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460885(CHEMBL4227912)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418239(CHEMBL1765728)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418243(CHEMBL1765732)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460888(CHEMBL4227059)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460888(CHEMBL4227059)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460889(CHEMBL4226407)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460889(CHEMBL4226407)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181277(4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181291(4-{3-[2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-py...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460887(CHEMBL4228313)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50460887(CHEMBL4228313)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD14BNPubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418232(CHEMBL1765762)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418248(CHEMBL1765746)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetAurora kinase B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50418258(CHEMBL1765749)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
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