TargetBreast cancer type 1 susceptibility protein(Homo sapiens (Human))
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition of BRCA1 assessed as BRCT-BACH1 interactionMore data for this Ligand-Target Pair
TargetBreast cancer type 1 susceptibility protein(Homo sapiens (Human))
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataKi: 3.80E+4nMAssay Description:Inhibition of BRCA1 assessed as BRCT-BACH1 interactionMore data for this Ligand-Target Pair
TargetBreast cancer type 1 susceptibility protein(Homo sapiens (Human))
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataKi: 3.90E+4nMAssay Description:Inhibition of BRCA1 assessed as BRCT-BACH1 interactionMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of PDK1-mediated RSK phosphorylation at Ser221 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of PDK1-mediated RSK phosphorylation at Ser221 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human recombinant 5-HT2A receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced calcium release preincu...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
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