Compile Data Set for Download or QSAR
Found 137 with Last Name = 'grimaudo' and Initial = 's'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166145((3S,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166146((3S,6S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166135((3S,6S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166141((3S,6S)-3-[(4-Chloro-phenyl)-phenyl-methoxy]-6-met...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50366775(BENZTROPINE | Benzatropine)copy SMILEScopy InChI
Affinity DataIC50: 118nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166147((3S,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166151((3S,6S)-3-Benzhydryloxy-6-methoxy-8-methyl-8-aza-b...)copy SMILEScopy InChI
Affinity DataIC50: 276nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166145((3S,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166150((3S,6S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166143((3S,6S)-3-[(4-Chloro-phenyl)-phenyl-methoxy]-6-met...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166144((3S,6S)-3-[(4-Chloro-phenyl)-phenyl-methoxy]-8-met...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026641(CHEMBL3335367)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166136((R)-6-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50135180(CHEMBL3746143)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97GZPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166140((S)-6-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166139((3S,6S)-3-Benzhydryloxy-8-methyl-8-aza-bicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50135175(CHEMBL490384)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97GZPubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50135177(CHEMBL3747558)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97GZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166140((S)-6-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166137((3S,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166137((3S,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166142((3S,6S)-3-Benzhydryloxy-6-methoxymethoxy-8-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMedDrugBank
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186763(4,3'',5''-trimethoxy-[1,1';2',1'']-terphenyl | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026644(CHEMBL3335370)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM23928(1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]be...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186757(CHEMBL208098 | [1,1';2',1'']-terphenyl-4,3'',5''-t...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186764(2-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-6-methoxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026642(CHEMBL3335368)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026643(CHEMBL3335369)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM23928(1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]be...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50131688((E)-4-(3,5-dimethoxystyryl)phenol | 3,5-Dimethoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186761(4,3'',5''-trimethoxy-[1,1';3',1'']-terphenyl | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universit£ di Ferrara

Curated by ChEMBL
LigandPNGBDBM50166146((3S,6S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M8MPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186757(CHEMBL208098 | [1,1';2',1'']-terphenyl-4,3'',5''-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186750(3'',5''-dimethoxy-[1,1';3',1'']-terphenyl-4-ol | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186755(3'',5''-dimethoxy-[1,1';2',1'']-terphenyl-4-ol | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50026629(CHEMBL3334509)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V70PubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186758(6-(3,5-dimethoxy-phenyl)-naphthalen-2-ol | CHEMBL3...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186763(4,3'',5''-trimethoxy-[1,1';2',1'']-terphenyl | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186751(4-chloro-2-[(E)-2-(3,5-dimethoxy-phenyl)-vinyl]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£ di Bologna

Curated by ChEMBL
LigandPNGBDBM50186756(5-[(E)-2-(3,5-dimethoxy-phenyl)-vinyl]-2-ethoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RKZPubMed
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