Compile Data Set for Download or QSAR
Found 22 with Last Name = 'hammelmann' and Initial = 's'
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459845(CHEMBL4227437)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459842(CHEMBL4228286)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148782(CHEMBL3770049)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459841(CHEMBL4225467)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459843(CHEMBL4225505)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459844(CHEMBL4227975)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148776(CHEMBL3769988)copy SMILEScopy InChI
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459842(CHEMBL4228286)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459845(CHEMBL4227437)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459845(CHEMBL4227437)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His10-tagged Sirt3 (118 to 395 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459843(CHEMBL4225505)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148776(CHEMBL3769988)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148782(CHEMBL3770049)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His10-tagged Sirt3 (118 to 395 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459844(CHEMBL4227975)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459841(CHEMBL4225467)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged Sirt1 (133 to 747 residues) using Z-(Ac)Lys-AMC as substrate measured after 4 hrs by high-throughput fluor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459843(CHEMBL4225505)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His10-tagged Sirt3 (118 to 395 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459842(CHEMBL4228286)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His10-tagged Sirt3 (118 to 395 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50459841(CHEMBL4225467)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His10-tagged Sirt3 (118 to 395 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50148776(CHEMBL3769988)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His10-tagged Sirt3 (118 to 395 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B33Z7PubMed