Compile Data Set for Download or QSAR
Found 217 with Last Name = 'hjorth' and Initial = 's'
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Mutant factor of the compound against mu-[K303E] with Opioid receptor kappa 1 for binding affinityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expresse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expresse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50087456(17-Methyl-17'-cyclopropylmethyl-3'-hydroxy-6,6',7,...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against K303E Opioid receptor mu 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expresse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor mu 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Mutant factor against mu-[K303E] with Opioid receptor kappa 1 for binding affinityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50087456(17-Methyl-17'-cyclopropylmethyl-3'-hydroxy-6,6',7,...)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against K303E Opioid receptor mu 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297K mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297A mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50087460(17-cyclopropylmethyl-17'-cyclopropylmethyl-3'-hydr...)copy SMILEScopy InChI
Affinity DataKi:  0.390nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50036286((R)-(-)-10-methyl-11-hydroxyaporphine | (R)-6,10-d...)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:Ability to displace [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1BQHPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50036286((R)-(-)-10-methyl-11-hydroxyaporphine | (R)-6,10-d...)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50087458(17-Cyclopropylmethyl-17'-guanidinyl-6,6',7,7'-tetr...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor kappa 1r in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  0.770nMAssay Description:Mutant factor against mu-[K303E] with Opioid receptor kappa 1 for binding affinityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  0.940nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against K303E Opioid receptor mu 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052869((R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibe...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50051944(3-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligand; range=2.2-3.2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1ZWNPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50087460(17-cyclopropylmethyl-17'-cyclopropylmethyl-3'-hydr...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against K303E Opioid receptor mu 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052859((R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50051945(2-((1S,2R)-2-Dipropylamino-cyclopropyl)-4-fluoro-p...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=2.7-3.6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1ZWNPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Effect on binding affinity of mutational exchange of Lys303 in the Opioid receptor mu 1 in transiently expressed rat cos-7 cells activity expressed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052864((R)-11-Ethyl-6-methyl-5,6,6a,7-tetrahydro-4H-diben...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50011264(2-(2-Dipropylamino-cyclopropyl)-phenol; hydrobromi...)copy SMILEScopy InChI
Affinity DataKi:  4.90nMAssay Description:In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=4.6-5.2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1ZWNPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016007((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...)copy SMILEScopy InChI
Affinity DataKi:  5.10nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052873((R)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052863((R)-6-Methyl-11-vinyl-5,6,6a,7-tetrahydro-4H-diben...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052848((R)-11-Methoxy-6,10-dimethyl-5,6,6a,7-tetrahydro-4...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052875(CHEMBL333836 | Trifluoro-methanesulfonic acid (R)-...)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052871((R)-11-Methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)copy SMILEScopy InChI
Affinity DataKi:  9.20nMAssay Description:Effect on binding affinity of mutational exchange of Lys303 in the Opioid receptor mu 1 in transiently expressed rat cos-7 cells activity expressed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052846((R)-10-Ethyl-6-methyl-5,6,6a,7-tetrahydro-4H-diben...)copy SMILEScopy InChI
Affinity DataKi:  9.20nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016013((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)copy SMILEScopy InChI
Affinity DataKi:  9.60nMAssay Description:Ability to displace [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1BQHPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016013((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)copy SMILEScopy InChI
Affinity DataKi:  9.60nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016013((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)copy SMILEScopy InChI
Affinity DataKi:  9.60nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052856((R)-11-Methoxy-10-methyl-6-propyl-5,6,6a,7-tetrahy...)copy SMILEScopy InChI
Affinity DataKi:  10.8nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50051959(CHEMBL35584 | Dipropyl-((1R,2R)-2-thiophen-2-yl-cy...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=12-14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1ZWNPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052851((R)-10-Methyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibe...)copy SMILEScopy InChI
Affinity DataKi:  12.3nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052855((R)-11-Methoxy-10-methyl-5,6,6a,7-tetrahydro-4H-di...)copy SMILEScopy InChI
Affinity DataKi:  12.6nMAssay Description:In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HXSPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM84636(CHEMBL27559 | NPA-11-OH-R,(+))copy SMILEScopy InChI
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]-raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  12.8nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297A mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  12.9nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297K mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3T23PubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50051946(CHEMBL37503 | Dipropyl-(2-thiophen-2-yl-cyclopropy...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=12-14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1ZWNPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50052867((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...)copy SMILEScopy InChI
Affinity DataKi:  14.4nMAssay Description:In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43S6SPubMed
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