Compile Data Set for Download or QSAR
Found 318 with Last Name = 'kuroda' and Initial = 's'
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467841(CHEMBL4284073)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467845(CHEMBL4288518)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50315418((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467849(CHEMBL4280615)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467850(CHEMBL4290854)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50402251(CHEMBL2204791)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082W9PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50450928(CHEMBL2113728)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against Adenosine A1 Receptor using [3H]-CHA in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JK6PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467840(CHEMBL4286329)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467843(CHEMBL4290434)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against Adenosine A1 Receptor using [3H]-CHA in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JK6PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467842(CHEMBL4289746)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467851(CHEMBL4290161)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467854(CHEMBL4291937)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467855(CHEMBL4279495)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467847(CHEMBL4287309)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467848(CHEMBL4281880)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50444445(CHEMBL3092373)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082W9PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467846(CHEMBL4282565)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetBeta-glucuronidase(Homo sapiens (Human))TBA
LigandPNGBDBM50405568(CHEMBL5273557)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:In vitro concentration required to inhibit partially purified dihydropteroate synthase of Escherichia coli by 50%More data for this Ligand-Target Pair
In DepthDetails
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503838(CHEMBL4450704)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50079655(CHEMBL294302 | {2-[6-Oxo-3-(2-phenyl-pyrazolo[1,5-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against Adenosine A1 Receptor using [3H]-CHA in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JK6PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50444447(CHEMBL3092365)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082W9PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50079650(CHEMBL59673 | FR-166124 | {2-[6-Oxo-3-(2-phenyl-py...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Adenosine A1 Receptor using [3H]-CHA in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JK6PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50079649(CHEMBL59466 | {2-[6-Oxo-3-(2-phenyl-pyrazolo[1,5-a...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against Adenosine A1 Receptor using [3H]-CHA in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JK6PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50444444(CHEMBL3092375)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082W9PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Adenosine A1 Receptor using [3H]-CHA in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JK6PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503834(CHEMBL4591009)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503827(CHEMBL4439652)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50315435((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-hydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503822(CHEMBL4460788)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503841(CHEMBL4554040)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503835(CHEMBL4524341)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503838(CHEMBL4450704)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467854(CHEMBL4291937)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503822(CHEMBL4460788)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467845(CHEMBL4288518)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503832(CHEMBL4514344)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetBifunctional protein GlmU(Escherichia coli)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50102673(CHEMBL3341771)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of Escherichia coli ATCC 27325 GlmU expressed in Escherichia coli HMS174(DE3) incubated for 15 mins prior to MgCl2 addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BR9PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503837(CHEMBL4516721)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetAurora kinase B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50102663(CHEMBL3343037)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human AURKB incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BR9PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467847(CHEMBL4287309)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50444446(CHEMBL3092367)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082W9PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503823(CHEMBL4452698)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503841(CHEMBL4554040)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50444443(CHEMBL3092376)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082W9PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503823(CHEMBL4452698)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467853(CHEMBL4282961)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50467841(CHEMBL4284073)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XWKPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503840(CHEMBL4551742)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50503825(CHEMBL4564494)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63R7FPubMed
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