Compile Data Set for Download or QSAR
Found 515 with Last Name = 'manns' and Initial = 's'
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)copy SMILEScopy InChI
Affinity DataKi:  0.00680nMAssay Description:Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...More data for this Ligand-Target Pair
TargetTolloid-like protein 1(Homo sapiens)
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)copy SMILEScopy InChI
Affinity DataKi:  0.0310nMAssay Description:Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
TargetTolloid-like protein 2(Homo sapiens)
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)copy SMILEScopy InChI
Affinity DataKi:  0.0390nMAssay Description:Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546794(CHEMBL4777335)copy SMILES
Affinity DataKi:  0.0900nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546794(CHEMBL4777335)copy SMILES
Affinity DataKi:  0.0900nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546795(CHEMBL4777740)copy SMILES
Affinity DataKi:  0.200nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546795(CHEMBL4777740)copy SMILES
Affinity DataKi:  0.200nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetTolloid-like protein 1(Homo sapiens)
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)copy SMILEScopy InChI
Affinity DataKi:  0.240nMAssay Description:Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546796(CHEMBL4761229)copy SMILES
Affinity DataKi:  0.25nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546796(CHEMBL4761229)copy SMILES
Affinity DataKi:  0.25nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetTolloid-like protein 2(Homo sapiens)
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546797(CHEMBL4757049)copy SMILES
Affinity DataKi:  290nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546797(CHEMBL4757049)copy SMILES
Affinity DataKi:  290nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546800(CHEMBL4758443)copy SMILES
Affinity DataKi:  345nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546800(CHEMBL4758443)copy SMILES
Affinity DataKi:  345nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546798(CHEMBL4779026)copy SMILES
Affinity DataKi:  700nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546798(CHEMBL4779026)copy SMILES
Affinity DataKi:  700nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546799(CHEMBL4755678)copy SMILES
Affinity DataKi:  800nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetCathepsin S(Homo sapiens (Human))TBA
LigandPNGBDBM50546799(CHEMBL4755678)copy SMILES
Affinity DataKi:  800nMAssay Description:Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NVMPubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458775(CHEMBL4218415)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458774(CHEMBL4202714)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458773(CHEMBL4204567)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458765(CHEMBL4205697)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458764(CHEMBL4209125)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458763(CHEMBL4202848)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50439218(CHEMBL2418809)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319X9HPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294706(4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetraz...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296010(2-isobutyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03VCPubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458758(CHEMBL4207907)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35127PubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50298210((S)-2-chloro-4-((2,5-dichlorobenzyl)(1-ethyl-5-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G9TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50298207((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropyl-5-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G9TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50298208((S)-2-chloro-4-((2-chloro-5-fluorobenzyl)(1-ethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G9TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294715(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294702(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)e...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294703(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03VCPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294705(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294696(4-((2-chlorobenzyl)(1-(2-methylthiazol-4-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50298219((R)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G9TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50298209((S)-2-chloro-4-((1-ethyl-5-oxopyrrolidin-3-yl)(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G9TPubMed
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50439217(CHEMBL2418811)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319X9HPubMed
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50439220(CHEMBL2418807)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319X9HPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294707(4-((2-chlorobenzyl)(1-(1-ethyl-1H-tetrazol-5-yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294710(2-chloro-4-(isobutyl(3-methyl-1-(1-methyl-1H-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294712((S)-2-chloro-4-((cyclobutylmethyl)(3-methyl-1-(1-m...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294714(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79GMPubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296009(2-ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03VCPubMed
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