Compile Data Set for Download or QSAR
Found 24 with Last Name = 'mateo-lozano' and Initial = 's'
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 73nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 75nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27220((2S)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 230nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 320nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 330nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universite de Lyon

LigandPNGBDBM27218((2R)-2-({4-[(3-chlorophenyl)amino]-8-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed