Compile Data Set for Download or QSAR
Found 286 with Last Name = 'mesch' and Initial = 's'
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639340(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-{[(5-chloro-2...)copy SMILES
Affinity DataIC50: 0.450nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639343(3-(1-Methyl-1H-imidazol-2-yl)propyl 3-[(5-chloroth...)copy SMILES
Affinity DataIC50: 0.480nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.490nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)copy SMILES
Affinity DataIC50: 0.490nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.510nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639346(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.520nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639322(Methyl 3-[(5-chlorothiophene-2-carbonyl)amino]-N-[...)copy SMILES
Affinity DataIC50: 0.540nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.560nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639344(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.610nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639342(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-{[(5-chloro-2...)copy SMILES
Affinity DataIC50: 0.630nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.660nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639346(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.680nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639338(Methyl 3-[(5-chlorothiophene-2-carbonyl)amino]-N-{...)copy SMILES
Affinity DataIC50: 0.680nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.710nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639342(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-{[(5-chloro-2...)copy SMILES
Affinity DataIC50: 0.740nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639339(Methyl 3-[(5-chlorothiophene-2-carbonyl)amino]-N-{...)copy SMILES
Affinity DataIC50: 0.760nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.780nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.780nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639348(3-(1-Methyl-1H-imidazol-2-yl)propyl 3-[(5-chloroth...)copy SMILES
Affinity DataIC50: 0.790nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639341(2-(1-Methyl-1H-imidazol-5-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.830nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.850nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639341(2-(1-Methyl-1H-imidazol-5-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 0.890nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639347(3-(1-Methyl-1H-imidazol-2-yl)propyl 3-[(5-chloroth...)copy SMILES
Affinity DataIC50: 0.930nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639345(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639319(2-(Dimethylamino)ethyl 3-{[(5-chloro-2-thienyl)car...)copy SMILES
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639340(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-{[(5-chloro-2...)copy SMILES
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639343(3-(1-Methyl-1H-imidazol-2-yl)propyl 3-[(5-chloroth...)copy SMILES
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506203(CHEMBL4452312)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506156(CHEMBL4471140)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetCoagulation factor X(Homo sapiens (Human))TBA
LigandPNGBDBM639320(1-Methylpiperidin-4-yl 3-{[(5-chloro-2-thienyl)car...)copy SMILES
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639346(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 4.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 4.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639346(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 4.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506173(CHEMBL4589444)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639349(2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-[(5-chlorothi...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506179(CHEMBL4579583)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506184(CHEMBL4447043)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639322(Methyl 3-[(5-chlorothiophene-2-carbonyl)amino]-N-[...)copy SMILES
Affinity DataIC50: 9.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506187(CHEMBL4522504)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM639348(3-(1-Methyl-1H-imidazol-2-yl)propyl 3-[(5-chloroth...)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506180(CHEMBL4556573)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50506201(CHEMBL4516176)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048RWPubMed
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