Compile Data Set for Download or QSAR
Found 200 with Last Name = 'muppa' and Initial = 's'
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50579244(Avoralstat | BCX-4161)copy SMILES
Affinity DataKi:  0.260nMAssay Description:Inhibition of purified human plasma kallikrein assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Inhibition of purified human plasma kallikrein assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CW8PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416981((+)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-3-yl)pr...)copy SMILEScopy InChI
Affinity DataIC50: 0.660nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416981((+)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-3-yl)pr...)copy SMILEScopy InChI
Affinity DataIC50: 0.660nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.880nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417023((+)-N-(5-(1-amino-1-(4-carbamoylphenyl)-3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50607250(CHEMBL5219146)copy SMILES
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM50607250(CHEMBL5219146)copy SMILES
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416897(1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl-1-hy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416773(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417031((+)-N-(5-(1-amino-3-cyclopropyl-1-(2-methylpyridin...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417031((+)-N-(5-(1-amino-3-cyclopropyl-1-(2-methylpyridin...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417014((+-)-N-(5-(1-amino-1-(3-carbamoylphenyl)-3-cyclopr...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416975((+-)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-2-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416774(1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl-1-hy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416975((+-)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-2-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416996((+)-N-(5-(1-amino-1-(3-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416996((+)-N-(5-(1-amino-1-(3-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417024((+)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-4-yl)pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417024((+)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-4-yl)pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417021((+)-5-(1-amino-1-(3-(1-(3-(aminomethyl)phenyl)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416926((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416770(Racemic 1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416987((+-)-N-(5-(1-amino-3-cyclopropyl-1-phenylpropyl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416987((+-)-N-(5-(1-amino-3-cyclopropyl-1-phenylpropyl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417021((+)-5-(1-amino-1-(3-(1-(3-(aminomethyl)phenyl)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417008((+)-N-(5-(1-amino-1-(6-cyanopyridin-2-yl)-3-cyclop...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416909(1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl-1-hy...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417031((+)-N-(5-(1-amino-3-cyclopropyl-1-(2-methylpyridin...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417024((+)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-4-yl)pr...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417024((+)-N-(5-(1-amino-3-cyclopropyl-1-(pyridin-4-yl)pr...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416996((+)-N-(5-(1-amino-1-(3-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416996((+)-N-(5-(1-amino-1-(3-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416938((+-)-1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416897(1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl-1-hy...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416897(1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl-1-hy...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM417023((+)-N-(5-(1-amino-1-(4-carbamoylphenyl)-3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416774(1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl-1-hy...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416774(1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl-1-hy...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416938((+-)-1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416938((+-)-1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416796(1-(3-(aminomethyl)phenyl)-N-(5-(((cyclopropylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of purified human plasma kallikrein using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7288PubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM439347(US10633345, Compound 41e | US10689346, Compound 41...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416770(Racemic 1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))TBA
LigandPNGBDBM416770(Racemic 1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
Displayed 1 to 50 (of 200 total ) | Next | Last >>
Jump to: