Compile Data Set for Download or QSAR
Found 175 with Last Name = 'niwas' and Initial = 's'
TargetPurine nucleoside phosphorylase(Mus musculus)
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Binding affinity against Purine nucleoside Phosphorylase from calf spleenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50033666(2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methox...)copy SMILEScopy InChI
Affinity DataKi:  8.70nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50033666(2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methox...)copy SMILEScopy InChI
Affinity DataKi:  8.70nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50033666(2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methox...)copy SMILEScopy InChI
Affinity DataKi:  8.70nMAssay Description:Binding affinity against hydrophobic pocket of Purine nucleoside PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046234(2-Amino-7-benzyl-3,4a,5,7a-tetrahydro-pyrrolo[3,2-...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046239(2-Amino-9-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039551(CHEMBL13448 | [5-(2-Amino-6-oxo-1,6-dihydro-purin-...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046234(2-Amino-7-benzyl-3,4a,5,7a-tetrahydro-pyrrolo[3,2-...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50022243(2,8-Diamino-1,9-dihydro-purin-6-one | 8-AMINOGUANI...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039559(CHEMBL267803 | [5-(2-Amino-6-oxo-1,6-dihydro-purin...)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50005799(2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one | CHE...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039552(CHEMBL267312 | [3,3-Dimethyl-5-(6-oxo-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039555(CHEMBL13130 | [5-(6-Oxo-1,6-dihydro-purin-9-yl)-pe...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046226(2-Amino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50200094(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039554(8-Amino-1,7-dihydro-purin-6-one | CHEMBL83601)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21868(2-amino-9-(4-hydroxybutyl)-6,9-dihydro-3H-purin-6-...)copy SMILEScopy InChI
Affinity DataKi:  7.70E+4nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039550(9-(2-Amino-3,4-dihydroxy-butyl)-1,9-dihydro-purin-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039543(8-Amino-9-benzyl-1,9-dihydro-purin-6-one | CHEMBL8...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039560(9-(4-Hydroxy-butyl)-1,9-dihydro-purin-6-one | CHEM...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+5nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046227(2-Amino-6-thiophen-2-ylmethyl-3,7-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046231(2-Amino-6-furan-2-ylmethyl-3,7-dihydro-pyrrolo[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 0.0570nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046249(2-Amino-6-thiophen-3-ylmethyl-3,7-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046239(2-Amino-9-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046252(2-Amino-6-benzyl-3,7-dihydro-pyrrolo[3,2-d]pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 0.0850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046224(2-Amino-8-[(thiophen-3-ylmethyl)-amino]-1,9-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.0850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046246(2-Amino-8-[(thiophen-2-ylmethyl)-amino]-1,9-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046229(2-Amino-6-pyridin-3-yl-3,7-dihydro-pyrrolo[3,2-d]p...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046241(2-Amino-8-[(furan-2-ylmethyl)-amino]-1,9-dihydro-p...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046251(2-Amino-8-benzylamino-1,9-dihydro-purin-6-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046221(2-Amino-6-[(thiophen-3-ylmethyl)-amino]-3,7-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046238(2,8-Diamino-9-thiophen-3-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046216(2-Amino-6-[(furan-2-ylmethyl)-amino]-3,7-dihydro-p...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046223(2-Amino-6-benzylamino-3,7-dihydro-pyrrolo[3,2-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046243(2-Amino-6-[(thiophen-2-ylmethyl)-amino]-3,7-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046218(2-Amino-6-[(3-methyl-thiophen-2-ylmethyl)-amino]-3...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046248(2-Amino-8-[(3-methyl-thiophen-2-ylmethyl)-amino]-1...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078452((S)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039561(3-(3-Chloro-phenyl)-3-(4-oxo-4,5-dihydro-3H-pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048044(2-Amino-7-(tetrahydro-thiophen-2-ylmethyl)-3,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046236(2-Amino-8-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046254(2-Amino-8-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046226(2-Amino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042799(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
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