TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: <0.100nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Compound was assayed for inhibition against HIV protease activityMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Compound was assayed for inhibition against HIV protease activityMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Compound was assayed for inhibition against HIV protease activityMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Compound was assayed for inhibition against HIV protease activityMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Compound was assayed for inhibition against HIV protease activityMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of p38alpha by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 104nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 125nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 173nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 185nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of p38beta using KRELVEPLTPSGEAPNQALLR as substrate for 10 mins by lactate dehydrogenase-coupled spectrophotometric assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of p38alpha by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Vertex Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair