Compile Data Set for Download or QSAR
Found 234 with Last Name = 'penco' and Initial = 's'
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308730(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308728(1-(4-((5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308726(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308726(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 0.590nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308727(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]AB-MECA from human recombinant A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]CCK-8 from human recombinant CCKA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute for Chemical and Biochem. Research

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82XFPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183594(CHEMBL203693 | c[RGDf-(S)-alpha-TfmV])copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308727(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308728(1-(4-((5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ronzoni Institute for Chemical and Biochem. Research

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82XFPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£ di Milano

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308729(4-(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£ di Milano

Curated by ChEMBL
LigandPNGBDBM27135(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183587(CHEMBL379911 | c[RGDf-(S,R)-alpha-Dfm-F])copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308722(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308724(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308725(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183582(CHEMBL413574 | c[RGDf-(S)-N-Me-alpha-TfmF])copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308725(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323051(1-Biphenyl-3-yl-ethanone, O-(1-naphthylaminocarbon...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183593(CHEMBL379056 | c[RGD-(S)-alpha-TfmfV])copy SMILEScopy InChI
Affinity DataIC50: 10.0nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183590(CHEMBL380434 | c(RGDfF))copy SMILEScopy InChI
Affinity DataIC50: 10.3nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta3 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308723(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308724(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183590(CHEMBL380434 | c(RGDfF))copy SMILEScopy InChI
Affinity DataIC50: 15.7nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323050(1-Biphenyl-3-yl-ethanone, O-(4-fluorophenylaminoca...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183582(CHEMBL413574 | c[RGDf-(S)-N-Me-alpha-TfmF])copy SMILEScopy InChI
Affinity DataIC50: 18.8nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta3 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 18.9nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta3 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183585(CHEMBL383747 | c(RGDfMeF))copy SMILEScopy InChI
Affinity DataIC50: 19.8nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta3 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183585(CHEMBL383747 | c(RGDfMeF))copy SMILEScopy InChI
Affinity DataIC50: 19.8nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308722(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323049(1-Biphenyl-3-yl-ethanone, O-(4-methoxyphenylaminoc...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308730(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£ di Milano

Curated by ChEMBL
LigandPNGBDBM50316226((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183592(CHEMBL204309 | c[RGDf-(S)-alpha-TfmF])copy SMILEScopy InChI
Affinity DataIC50: 35.5nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta3 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183594(CHEMBL203693 | c[RGDf-(S)-alpha-TfmV])copy SMILEScopy InChI
Affinity DataIC50: 36.3nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta3 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G.Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308729(4-(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute for Chemical and Biochem. Research

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC8 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82XFPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50183584(CHEMBL203077 | c[RGDf-(R)-alpha-TfmV])copy SMILEScopy InChI
Affinity DataIC50: 42.8nMAssay Description:Displacement of [125I]echistatin from AlphaVbeta5 integrin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160FDPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Universita di Milano

Curated by ChEMBL
LigandPNGBDBM50246572(4-(4-hydroxyphenyl)-2,3-bis(2-methoxyethylidene)-1...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant RET active protein (unknown origin) by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44X5PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308723(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SG2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ronzoni Institute for Chemical and Biochem. Research

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Università degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50323052(1-Biphenyl-3-yl-ethanone, O-(phenylaminocarbonyl)o...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V5BPubMed
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