Compile Data Set for Download or QSAR
Found 210 with Last Name = 're depaolini' and Initial = 's'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343559(1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329914(1-methyl-8-(5-(4-methylpiperazin-1-yl)-2-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343568(1-methyl-8-(5-(1-methyl-1,2,3,6-tetrahydropyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343569(9-methyl-2-(5-(1-methylpiperidin-4-yl)-2-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579779(CHEMBL5091519)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579781(CHEMBL5094847)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579782(CHEMBL5078600)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579773(CHEMBL5079663)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579777(CHEMBL5090932)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579771(CHEMBL5077194)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579769(CHEMBL5075042)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579780(CHEMBL5089356)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579775(CHEMBL5085262)copy SMILES
Affinity DataIC50: 28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579757(CHEMBL5084844)copy SMILES
Affinity DataIC50: 28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579770(CHEMBL5090132)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579785(CHEMBL5075110)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579786(CHEMBL5093152)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579774(CHEMBL5081222)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343560(1-(2-aminoethyl)-8-(5-(4-methylpiperazin-1-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579772(CHEMBL5088776)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579784(CHEMBL5091201)copy SMILES
Affinity DataIC50: 34nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579764(CHEMBL5086885)copy SMILES
Affinity DataIC50: 40nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343570(8-(5-(1-(3-(dimethylamino)propyl)piperidin-4-yl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579778(CHEMBL5078057)copy SMILES
Affinity DataIC50: 43nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343561(8-(5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343571((S)-1-methyl-8-(5-(pyrrolidine-2-carboxamido)-2-(t...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579758(CHEMBL5085127)copy SMILES
Affinity DataIC50: 49nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579783(CHEMBL5088850)copy SMILES
Affinity DataIC50: 49nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343562(1-(3-aminopropyl)-8-(5-(4-methylpiperazin-1-yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343564(8-(5-((2-(diethylamino)ethyl)(methyl)amino)-2-(tri...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579765(CHEMBL5089748)copy SMILES
Affinity DataIC50: 61nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343565(1-methyl-8-(5-(pyrrolidin-2-ylamino)-2-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329931(8-(5-amino-2-(trifluoromethoxy)phenylamino)-1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579766(CHEMBL5093251)copy SMILES
Affinity DataIC50: 88nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579776(CHEMBL5077317)copy SMILES
Affinity DataIC50: 97nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579767(CHEMBL5089440)copy SMILES
Affinity DataIC50: 104nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343566(1-methyl-8-(5-(3-(4-methylpiperazin-1-yl)propylami...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579759(CHEMBL5075746)copy SMILES
Affinity DataIC50: 111nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579760(CHEMBL5085340)copy SMILES
Affinity DataIC50: 126nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579761(CHEMBL5087533)copy SMILES
Affinity DataIC50: 138nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579768(CHEMBL5094938)copy SMILES
Affinity DataIC50: 146nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329935(1-methyl-8-(5-(2-(1-methylpyrrolidin-2-yl)ethylami...)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579762(CHEMBL5086986)copy SMILES
Affinity DataIC50: 151nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329931(8-(5-amino-2-(trifluoromethoxy)phenylamino)-1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of PLK3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343567((R)-8-(5-(2-(hydroxymethyl)-4-methylpiperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343557((S)-8-(5-(2-(hydroxymethyl)-4-methylpiperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343558(1-methyl-8-(5-(1-methylpiperidine-4-carboxamido)-2...)copy SMILEScopy InChI
Affinity DataIC50: 224nMAssay Description:Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579741(CHEMBL5076272)copy SMILES
Affinity DataIC50: 227nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579729(CHEMBL5092659)copy SMILES
Affinity DataIC50: 236nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50343565(1-methyl-8-(5-(pyrrolidin-2-ylamino)-2-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 239nMAssay Description:Inhibition of PLK3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M088WPubMed
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