Compile Data Set for Download or QSAR
Found 33 with Last Name = 'thon' and Initial = 's'
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMedDrugBank
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Mahidol University

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human HMGR catalytic domain using 800 uM HMG-CoA as substrate measured every 20 secs for 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04R4PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM50576415(CHEMBL4852023)copy SMILES
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM50576410(CHEMBL4875917)copy SMILES
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM50576414(CHEMBL4874928)copy SMILES
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM50576413(CHEMBL4863718)copy SMILES
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM50576412(CHEMBL4859743)copy SMILES
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMed
TargetAromatase(Homo sapiens (Human))TBA
LigandPNGBDBM50576411(CHEMBL4866633)copy SMILES
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PQ1PubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Prince of Songkla University

Curated by ChEMBL
LigandPNGBDBM50463448(CHEMBL4243267)copy SMILEScopy InChI
Affinity DataIC50: 5.86E+4nMAssay Description:Inhibition of CFTR-mediated forskolin-induced chloride secretion in human T84 cells after 15 mins by short-circuit current analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0X4DPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50191275(CHEMBL3986260)copy SMILEScopy InChI
Affinity DataIC50: 3.87E+5nMAssay Description:Inhibition of human HMGR catalytic domain using 800 uM HMG-CoA as substrate measured every 20 secs for 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04R4PubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526580(CHEMBL4549036)copy SMILEScopy InChI
Affinity DataEC50:  530nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81289(Adenosine 3',5'-cyclic monophosphate sodiu...)copy SMILEScopy InChI
Affinity DataEC50:  3.87E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81289(Adenosine 3',5'-cyclic monophosphate sodiu...)copy SMILEScopy InChI
Affinity DataEC50:  5.62E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
LigandPNGBDBM50526578(CHEMBL4468490)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Activation of recombinant mouse HCN2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude at -30 mV holding potential by patc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)copy SMILEScopy InChI
Affinity DataEC50:  2.36E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526580(CHEMBL4549036)copy SMILEScopy InChI
Affinity DataEC50:  6.40E+3nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81292(8-Bromoadenosine 3',5'-cyclic monophosphat...)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)copy SMILEScopy InChI
Affinity DataEC50:  2.54E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)copy SMILEScopy InChI
Affinity DataEC50:  540nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526580(CHEMBL4549036)copy SMILEScopy InChI
Affinity DataEC50:  630nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81292(8-Bromoadenosine 3',5'-cyclic monophosphat...)copy SMILEScopy InChI
Affinity DataEC50:  780nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526578(CHEMBL4468490)copy SMILEScopy InChI
Affinity DataEC50:  2.75E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526580(CHEMBL4549036)copy SMILEScopy InChI
Affinity DataEC50:  300nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81289(Adenosine 3',5'-cyclic monophosphate sodiu...)copy SMILEScopy InChI
Affinity DataEC50:  4.98E+3nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526578(CHEMBL4468490)copy SMILEScopy InChI
Affinity DataEC50:  360nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)copy SMILEScopy InChI
Affinity DataEC50:  120nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81289(Adenosine 3',5'-cyclic monophosphate sodiu...)copy SMILEScopy InChI
Affinity DataEC50:  5.31E+4nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81292(8-Bromoadenosine 3',5'-cyclic monophosphat...)copy SMILEScopy InChI
Affinity DataEC50:  1.54E+4nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526578(CHEMBL4468490)copy SMILEScopy InChI
Affinity DataEC50:  2.06E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetCyclic nucleotide-gated olfactory channel(Rattus norvegicus)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526578(CHEMBL4468490)copy SMILEScopy InChI
Affinity DataEC50:  2.08E+3nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM81292(8-Bromoadenosine 3',5'-cyclic monophosphat...)copy SMILEScopy InChI
Affinity DataEC50:  1.09E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GTHPubMed