Compile Data Set for Download or QSAR
Found 57 with Last Name = 'wada' and Initial = 's'
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460520(CHEMBL4228293)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460521(CHEMBL4228332)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460518(CHEMBL4228977)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460523(CHEMBL4225627)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460524(CHEMBL4225893)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460518(CHEMBL4228977)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460522(CHEMBL4226829)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460521(CHEMBL4228332)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460523(CHEMBL4225627)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460520(CHEMBL4228293)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460517(CHEMBL4227185)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50474910(CHEMBL189836)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BDQPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268191(CHEMBL4102765)copy SMILEScopy InChI
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460524(CHEMBL4225893)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460522(CHEMBL4226829)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50460517(CHEMBL4227185)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
TargetHistone deacetylase 6(Mus musculus)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kindai University

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50377927(Clerodol | Fagarasterol | Farganasterol | LUPEOL |...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92C63PubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50260250(CHEMBL491188 | Olean-12-en-3beta,15alpha-diol)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92C63PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50474907(CHEMBL193251)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BDQPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268184(CHEMBL4060026)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50474904(CHEMBL191216)copy SMILEScopy InChI
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BDQPubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50474909(CHEMBL189793)copy SMILEScopy InChI
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BDQPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50460525(CHEMBL4228731)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268190(CHEMBL4099888)copy SMILEScopy InChI
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM23207((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymet...)copy SMILEScopy InChI
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92C63PubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50260252(CHEMBL489552 | olean-12-en-3bea,15alpha,24-triol)copy SMILEScopy InChI
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92C63PubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50250882((23R,25R)-3,4-seco-9beta-H-lanosta-4(28),7-dien-26...)copy SMILEScopy InChI
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8RMHPubMed
TargetSensor histidine kinase WalK(Bacillus subtilis (strain 168))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50371212(CHEMBL394220)copy SMILEScopy InChI
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Bacillus subtilis histidine kinase YycGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40CZPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 5.04E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50250883((2R,4S,6R)-6-((3R,3aR,5aS,6S,7S,9bR)-6-(3-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 5.04E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8RMHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50460519(CHEMBL4226061)copy SMILEScopy InChI
Affinity DataIC50: 5.53E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21WVPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268187(CHEMBL4104323)copy SMILEScopy InChI
Affinity DataIC50: 5.57E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
TargetSensor histidine kinase WalK(Bacillus subtilis (strain 168))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50371211(CHEMBL241735)copy SMILEScopy InChI
Affinity DataIC50: 6.35E+4nMAssay Description:Inhibition of Bacillus subtilis histidine kinase YycGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40CZPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268185(CHEMBL4088260)copy SMILEScopy InChI
Affinity DataIC50: 6.45E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50474905(CHEMBL426087)copy SMILEScopy InChI
Affinity DataIC50: 6.65E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BDQPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50250884((2R,6R)-methyl 6-((3R,3aR,5aS,6S,7S,9bR)-6-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8RMHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50250881(CHEMBL518106 | Methyl (23R,25R)-3,4-seco-9beta-H-l...)copy SMILEScopy InChI
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8RMHPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50474908(CHEMBL191001)copy SMILEScopy InChI
Affinity DataIC50: 8.32E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BDQPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268189(CHEMBL4081883)copy SMILEScopy InChI
Affinity DataIC50: 8.92E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Curated by ChEMBL
LigandPNGBDBM50268172(CHEMBL4061636)copy SMILEScopy InChI
Affinity DataIC50: 9.91E+4nMAssay Description:Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DWSPubMed
Displayed 1 to 50 (of 57 total ) | Next | Last >>
Jump to: