Compile Data Set for Download or QSAR
Found 342 with Last Name = 'de castro' and Initial = 's'
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612874(CHEMBL5269349)copy SMILES
Affinity DataKi:  200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612874(CHEMBL5269349)copy SMILES
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50187672(CHEMBL207209 | N-(3,4-dichloro-phenyl)-2-cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  4.69E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P60C6PubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612872(CHEMBL5284653)copy SMILES
Affinity DataKi:  7.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33960(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 reverse transcriptase polymerase p51/p66 after 10 to 20 mins in presence of [3H]-TTP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33953(dihydroxy benzoyl naphthyl hydrazone (DHBNH))copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using RNA-DNA hybrid duplex after 30 mins by FRET-based microplate fluorescence assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33959(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 reverse transcriptase polymerase p51/p66 after 10 to 20 mins in presence of [3H]-TTP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant HIV-1 BH10 reverse transcriptase p51/p66 expressed in Escherichia coli preincubated for 10 mins followed by D38/25PGA templ...More data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
Instituto de Tecnologia em F£rmacos - Farmanguinhos

Curated by ChEMBL
LigandPNGBDBM50386184(CHEMBL2042801)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59HTPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278343(CHEMBL4169040)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278343(CHEMBL4169040)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50267312(CHEMBL4105040)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant Leishmania infantum TryR preincubated for 10 mins followed by T[S]2 substrate addition and measured after 1 hr in presence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5B8SPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50267314(CHEMBL4076896)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR preincubated for 10 mins followed by T[S]2 substrate addition and measured after 1 hr in presence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5B8SPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278295(CHEMBL4172675)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50458301(CHEMBL4205871)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant Leishmania infantum trypanothione reductase using T[S]2 as substrate preincubated for 5 mins followed by substrate and NADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QD6PubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278296(CHEMBL4164582)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278281(CHEMBL4169921)copy SMILEScopy InChI
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612888(CHEMBL5266073)copy SMILES
Affinity DataIC50: 2.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612887(CHEMBL5282990)copy SMILES
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278340(CHEMBL4168013)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612873(CHEMBL5265836)copy SMILES
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612874(CHEMBL5269349)copy SMILES
Affinity DataIC50: 3.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278339(CHEMBL4163454)copy SMILEScopy InChI
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278341(CHEMBL4160088)copy SMILEScopy InChI
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278345(CHEMBL4159278)copy SMILEScopy InChI
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Trypanosoma congolense)TBA
LigandPNGBDBM50612874(CHEMBL5269349)copy SMILES
Affinity DataIC50: 3.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148760(CHEMBL3142914 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148764(CHEMBL3142919 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50148763(CHEMBL3142918 | [1-[2',5'-Bis-O-(tert-butyldimethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM50458413(CHEMBL3142917)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of HIV1 3B reverse transcriptase using polyC/oligo(dG12) as template/primer in presence of [3H]dGTP and calf thymus DNA after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50267313(CHEMBL4080816)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR preincubated for 10 mins followed by T[S]2 substrate addition and measured after 1 hr in presence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5B8SPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612876(CHEMBL5278754)copy SMILES
Affinity DataIC50: 3.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612886(CHEMBL5275080)copy SMILES
Affinity DataIC50: 3.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612882(CHEMBL5276918)copy SMILES
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612883(CHEMBL5281063)copy SMILES
Affinity DataIC50: 4.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Trypanosoma congolense)TBA
LigandPNGBDBM50612873(CHEMBL5265836)copy SMILES
Affinity DataIC50: 4.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50612874(CHEMBL5269349)copy SMILES
Affinity DataIC50: 4.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33959(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using RNA-DNA hybrid duplex after 30 mins by FRET-based microplate fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)TBA
LigandPNGBDBM50612873(CHEMBL5265836)copy SMILES
Affinity DataIC50: 5.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50267311(CHEMBL4070159)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR preincubated for 10 mins followed by T[S]2 substrate addition and measured after 1 hr in presence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5B8SPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278280(CHEMBL4172606)copy SMILEScopy InChI
Affinity DataIC50: 5.38E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612881(CHEMBL5280860)copy SMILES
Affinity DataIC50: 5.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612879(CHEMBL5279478)copy SMILES
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50458300(CHEMBL4215042)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of recombinant Leishmania infantum trypanothione reductase using T[S]2 as substrate preincubated for 5 mins followed by substrate and NADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QD6PubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50458299(CHEMBL4215578)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant Leishmania infantum trypanothione reductase using T[S]2 as substrate preincubated for 5 mins followed by substrate and NADP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5QD6PubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612884(CHEMBL5277682)copy SMILES
Affinity DataIC50: 6.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto de Qu£mica M£dica (IQM, CSIC)

Curated by ChEMBL
LigandPNGBDBM33960(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H using RNA-DNA hybrid duplex after 30 mins by FRET-based microplate fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79F0JPubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612875(CHEMBL5272155)copy SMILES
Affinity DataIC50: 7.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50612885(CHEMBL5287730)copy SMILES
Affinity DataIC50: 7.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50278294(CHEMBL4161951)copy SMILEScopy InChI
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of oxidoreductase activity of recombinant Leishmania infantum trypanothione reductase pre-incubated for 10 mins before T[S]2 and NADPH add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90C6JPubMed
Displayed 1 to 50 (of 342 total ) | Next | Last >>
Jump to: