Compile Data Set for Download or QSAR
Found 1470 with Last Name = 'patel' and Initial = 'sb'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250920(CHEMBL4078799)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250934(CHEMBL4066906)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM237874(US9394282, 9-9)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250922(CHEMBL4096821)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250923(CHEMBL4072848 | US10766883, Ex-3)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16015(CHEMBL252967 | N-cyclopropyl-4-[4-(3,4-dichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 0.0780nMpH: 7.0 T: 2°CAssay Description:HTRF relies on fluorescence resonance energy transfer (FRET) between the donor, a europium cryptate (EuK), and the acceptor, the light harvesting pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CWZPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122385(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50152595(CHEMBL3780091)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122387(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250927(CHEMBL4071005 | US10766883, Ex-1)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14 [G110A](Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM15240(4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250919(CHEMBL4102140)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122386(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM237869(US10766883, Comp. Ex-1 9-4 | US9394282, 9-4)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM15240(4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122390(5-(2-Chloro-4-fluoro-phenyl)-1-(2,6-dichloro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetMitogen-activated protein kinase 14 [G110D](Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM15240(4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM237900(US10766883, Comp. Ex-4 9-35 | US9394282, 9-35)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250931(CHEMBL4079092)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50371255(CHEMBL1203953)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27W4MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250928(CHEMBL4092626)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250938(CHEMBL4088262)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250920(CHEMBL4078799)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human TYK2 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50347672(CHEMBL1802904)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZFZPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM17060(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-(p...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122379(7-(1-tert-Butyl-piperidin-4-yl)-5-(2-chloro-4-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122384(5-(2-Chloro-phenyl)-1-(2,6-dichloro-phenyl)-7-(pip...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50374938(CHEMBL402163)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human recombinant DPP4 expressed in insect cellMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250930(CHEMBL4076473)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM237866(US9394282, 9-1)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [654-1073](Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15337((5R)-6-(4-{[2-(3-iodobenzyl)-3-oxocyclohex-1-en-1-...)copy SMILEScopy InChI
Affinity DataIC50: 0.270nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250918(CHEMBL4104623)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM147735(US8962608, 28-47)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122382(5-(2-Chloro-4-fluoro-phenyl)-7-[1-(1-cyclopropyl-e...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50152667(CHEMBL3780636)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6203PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232520((2R)-4-oxo-4-[3-(trifluoromethyl)-8-[2-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27W4MPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232520((2R)-4-oxo-4-[3-(trifluoromethyl)-8-[2-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27W4MPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232506(2-[7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butano...)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27W4MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:Inhibition of GST-tagged recombinant human JAK3 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.350nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6203PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50152602(CHEMBL3781442)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6203PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250935(CHEMBL4085737)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM50122377(5-(2-Chloro-4-fluoro-phenyl)-7-(1-cyclobutyl-piper...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2884PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM237902(US9394282, 9-37)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM237874(US9394282, 9-9)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human TYK2 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232518((2R)-4-oxo-4-[8-(pyridin-2-ylmethyl)-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27W4MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50250929(CHEMBL4066193 | US10875847, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867RDPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232518((2R)-4-oxo-4-[8-(pyridin-2-ylmethyl)-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27W4MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6203PubMedDrugBank
Displayed 1 to 50 (of 1470 total ) | Next | Last >>
Jump to: