Compile Data Set for Download or QSAR
Found 52 with Last Name = 'baker' and Initial = 'sc'
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31531(Substituted Benzamide Derivative, 2 | med.21724, C...)copy SMILEScopy InChI
Affinity DataIC50: 460nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)copy SMILEScopy InChI
Affinity DataIC50: 560nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31530(2-methyl-5-[(methylamino)methyl]-N-[(1R)-1-(naphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31528(Substituted Benzamide Derivative, 32)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31520(Naphthalene and Benzamide Derivative, 5h)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31524(5-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 2.64E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31527(Substituted Benzamide Derivative, 40)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31529(Substituted Benzamide Derivative, 47)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31526(Substituted Benzamide Derivative, 33)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31508(Substituted Benzamide Derivative, lead | med.21724...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477129(CHEMBL397154 | acs.jmedchem.1c00409_ST.512)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JC9PubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31525(Substituted Benzamide Derivative, 29 | med.21724, ...)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31514(Naphthyl and Benzamide Derivative, 5f)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31512(Substituted Benzamide Derivative, 5d)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31509(Substituted Benzamide Derivative, 5a)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477130(CHEMBL235873 | acs.jmedchem.1c00409_ST.563)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JC9PubMed
TargetReplicase polyprotein 1a(Human coronavirus NL63)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007789(CHEMBL1173044 | GRL-0667 | N-(2H-1,3-benzodioxol-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31521(Naphthalene and Benzamide Derivative, 21 | med.217...)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31522(Naphthalene and Benzamide Derivative, 23)copy SMILEScopy InChI
Affinity DataIC50: 2.48E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31510(Substituted Benzamide Derivative, 5b)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetUbiquitin carboxyl-terminal hydrolase 21(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007791(CHEMBL3233815 | med.21724, Compound 168)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human USP21 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 21(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human USP21 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 21(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007789(CHEMBL1173044 | GRL-0667 | N-(2H-1,3-benzodioxol-5...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human USP21 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 21(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007790(CHEMBL3233814 | med.21724, Compound 169)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human USP21 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1a(Human coronavirus NL63)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007791(CHEMBL3233815 | med.21724, Compound 168)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1a(Human coronavirus NL63)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007792(CHEMBL3233808)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1a(Human coronavirus NL63)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007793(CHEMBL3233813)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Purdue University

Curated by ChEMBL
LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory concentration required for antiviral activity against SARS-CoV 3CLpro proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3CVZPubMed
TargetReplicase polyprotein 1a(Human coronavirus NL63)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31516(Naphthyl and Benzamide Derivative, 9)copy SMILEScopy InChI
Affinity DataIC50: 4.61E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1a(Human coronavirus NL63)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007794(CHEMBL3233822)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50176014((S,E)-ethyl 4-((2R,5S)-6-methyl-2-(3-methylbut-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory concentration required for antiviral activity against SARS-CoV 3CLpro proteaseMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477128(CHEMBL238217 | GRL-0155S)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JC9PubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31511(Substituted Benzamide Derivative, 5c)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetUbiquitin carboxyl-terminal hydrolase 20(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007791(CHEMBL3233815 | med.21724, Compound 168)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP20 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 20(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007790(CHEMBL3233814 | med.21724, Compound 169)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP20 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 20(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP20 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007791(CHEMBL3233815 | med.21724, Compound 168)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP8 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007790(CHEMBL3233814 | med.21724, Compound 169)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP8 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP8 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007789(CHEMBL1173044 | GRL-0667 | N-(2H-1,3-benzodioxol-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP8 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP2 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human USP7 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DBMPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31513(Substituted Benzamide Derivative, 5e)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+5nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477127(CHEMBL393608)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JC9PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM11249(AG7088 analogue 2c | ethyl (2E,4S)-4-[(2S)-2-[(2S)...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JC9PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50176014((S,E)-ethyl 4-((2R,5S)-6-methyl-2-(3-methylbut-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JC9PubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31519(Naphthyl and Benzamide Derivative, 17 | racemic)copy SMILEScopy InChI
Affinity DatapH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31515(Naphthyl and Benzamide Derivative, 5g)copy SMILEScopy InChI
Affinity DatapH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8497ZPubMed
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