Compile Data Set for Download or QSAR
Found 69 with Last Name = 'issakani' and Initial = 'sd'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50249090(3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...)copy SMILEScopy InChI
Affinity DataKi:  96nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50249090(3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068649(CHEMBL3402361 | US10828301, Compound R921302)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM327998(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- cya...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM328001(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM328171(N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM328133(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(2,4- d...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM328006(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM327927(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM327927(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM328171(N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM328006(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM328133(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(2,4- d...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068649(CHEMBL3402361 | US10828301, Compound R921302)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in ionomycin-induced calcium mobilization mediated degranulation by tryptase rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068650(CHEMBL3402403)copy SMILEScopy InChI
Affinity DataEC50:  1.29E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068653(CHEMBL3402402)copy SMILEScopy InChI
Affinity DataEC50:  210nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068660(CHEMBL3402401)copy SMILEScopy InChI
Affinity DataEC50:  400nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068662(CHEMBL3402400)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068777(CHEMBL3402399)copy SMILEScopy InChI
Affinity DataEC50:  280nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068778(CHEMBL3402398)copy SMILEScopy InChI
Affinity DataEC50:  430nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068779(CHEMBL3402397 | US10828301, Compound R945071 | US9...)copy SMILEScopy InChI
Affinity DataEC50:  210nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068795(CHEMBL3402396)copy SMILEScopy InChI
Affinity DataEC50:  1.55E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068797(CHEMBL3402395)copy SMILEScopy InChI
Affinity DataEC50:  450nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068798(CHEMBL3402394)copy SMILEScopy InChI
Affinity DataEC50:  530nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068799(CHEMBL3402393)copy SMILEScopy InChI
Affinity DataEC50:  760nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068800(CHEMBL3402391)copy SMILEScopy InChI
Affinity DataEC50:  490nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068801(CHEMBL3402390)copy SMILEScopy InChI
Affinity DataEC50:  440nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068802(CHEMBL3400172)copy SMILEScopy InChI
Affinity DataEC50:  4.15E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068803(CHEMBL3402389)copy SMILEScopy InChI
Affinity DataEC50:  930nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068804(CHEMBL3402388)copy SMILEScopy InChI
Affinity DataEC50:  290nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068805(CHEMBL3402387)copy SMILEScopy InChI
Affinity DataEC50:  330nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068806(CHEMBL3402386)copy SMILEScopy InChI
Affinity DataEC50:  670nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068807(CHEMBL3402385)copy SMILEScopy InChI
Affinity DataEC50:  940nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068855(CHEMBL3402384)copy SMILEScopy InChI
Affinity DataEC50:  430nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068856(CHEMBL3402383)copy SMILEScopy InChI
Affinity DataEC50:  370nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068857(CHEMBL3402380)copy SMILEScopy InChI
Affinity DataEC50:  380nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50249090(3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...)copy SMILEScopy InChI
Affinity DataEC50:  350nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM31853(2,4-Bisanilinopyrimidine, 18)copy SMILEScopy InChI
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068858(CHEMBL3402379)copy SMILEScopy InChI
Affinity DataEC50:  270nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068859(CHEMBL3402378)copy SMILEScopy InChI
Affinity DataEC50:  440nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068860(CHEMBL3402377)copy SMILEScopy InChI
Affinity DataEC50:  230nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068861(CHEMBL3402376)copy SMILEScopy InChI
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068862(CHEMBL3402375)copy SMILEScopy InChI
Affinity DataEC50:  5.80E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068863(CHEMBL3402374)copy SMILEScopy InChI
Affinity DataEC50:  900nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068864(CHEMBL3402373)copy SMILEScopy InChI
Affinity DataEC50:  500nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068865(CHEMBL3402372)copy SMILEScopy InChI
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068866(CHEMBL3402371)copy SMILEScopy InChI
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Amarit Bioscience, Inc.

Curated by ChEMBL
LigandPNGBDBM50068867(CHEMBL3402370)copy SMILEScopy InChI
Affinity DataEC50:  5.81E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SFKPubMed
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