Compile Data Set for Download or QSAR
Found 35 with Last Name = 'weeks' and Initial = 'sd'
TargetAspartate--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50339907(((S)-2-amino-3-carboxypropanoyl)(((2R,3S,4R,5R)-5-...)copy SMILEScopy InChI
Affinity DataKi:  0.0520nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Aspartyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheric...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458119(Leusa)copy SMILEScopy InChI
Affinity DataKi:  0.139nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
TargetSerine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50339906(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Seryl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichia...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458122(CHEMBL4204314)copy SMILEScopy InChI
Affinity DataKi:  0.654nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524451(CHEMBL4553017)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B73PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50222902(CHEMBL1163069)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569962(CHEMBL4864835)copy SMILES
Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458121(CHEMBL1163085)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Tyrosyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherich...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569952(CHEMBL4869028)copy SMILES
Affinity DataKi:  5.5nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524359(CHEMBL4465674)copy SMILEScopy InChI
Affinity DataKi:  9.80nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524360(CHEMBL3265242)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569957(CHEMBL4864965)copy SMILES
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524355(CHEMBL4467328)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetAspartate--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458117(CHEMBL4203761)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Aspartyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458118(CHEMBL4208126)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Tyrosyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherich...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524361(CHEMBL4451258)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569963(CHEMBL4855635)copy SMILES
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569960(CHEMBL4852287)copy SMILES
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569958(CHEMBL4864716)copy SMILES
Affinity DataKi:  32nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524357(CHEMBL4558119)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569954(CHEMBL4867227)copy SMILES
Affinity DataKi:  52nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524354(CHEMBL3265243)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50544145(CHEMBL4636583)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K4QPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569955(CHEMBL4876966)copy SMILES
Affinity DataKi:  108nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50544146(CHEMBL4648043)copy SMILEScopy InChI
Affinity DataKi:  114nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K4QPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524353(CHEMBL4518549)copy SMILEScopy InChI
Affinity DataKi:  149nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569961(CHEMBL4861722)copy SMILES
Affinity DataKi:  182nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458120(CHEMBL4215986)copy SMILEScopy InChI
Affinity DataKi:  213nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569956(CHEMBL4850408)copy SMILES
Affinity DataKi:  388nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetSerine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458116(CHEMBL4208640)copy SMILEScopy InChI
Affinity DataKi:  523nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Seryl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524358(CHEMBL4475568)copy SMILEScopy InChI
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569959(CHEMBL4871282)copy SMILES
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524356(CHEMBL4460886)copy SMILEScopy InChI
Affinity DataKi:  1.48E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50569953(CHEMBL4871079)copy SMILES
Affinity DataKi:  2.97E+3nMAssay Description:Inhibition of recombinant Escherichia coli LeuRS assessed as inhibition of 14C-radiolabelled leucine transfer to tRNA leucine preincubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93SZPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524451(CHEMBL4553017)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B73PubMed