TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL