Compile Data Set for Download or QSAR
Found 166 with Last Name = 'pearson' and Initial = 'se'
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 0.0631nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)copy SMILEScopy InChI
Affinity DataIC50: 0.138nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50084948(CHEMBL195515 | GW7604)copy SMILEScopy InChI
Affinity DataIC50: 0.145nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)copy SMILEScopy InChI
Affinity DataIC50: 0.209nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cells in presence of 0.25 uM tamoxifenMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 0.209nMAssay Description:Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)copy SMILEScopy InChI
Affinity DataIC50: 0.282nMAssay Description:Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)copy SMILEScopy InChI
Affinity DataIC50: 0.309nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125055(CHEMBL3623002)copy SMILEScopy InChI
Affinity DataIC50: 0.417nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125055(CHEMBL3623002)copy SMILEScopy InChI
Affinity DataIC50: 0.708nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)copy SMILEScopy InChI
Affinity DataIC50: 0.794nMAssay Description:Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)copy SMILEScopy InChI
Affinity DataIC50: 0.813nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125055(CHEMBL3623002)copy SMILEScopy InChI
Affinity DataIC50: 0.832nMAssay Description:Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)copy SMILEScopy InChI
Affinity DataIC50: 0.851nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50190001(CHEMBL213007 | N-(5-chloro-2-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50072961(CHEMBL3410672)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50371358(CHEMBL257478)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ebrB2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RSHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50190002(CHEMBL387265 | N-(3-chloro-2-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50190000(CHEMBL214798 | N-(3-chloro-2-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50189993(2-(4-(4-(3-chloro-2-fluorophenylamino)-7-methoxyqu...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50189995(CHEMBL213874 | N-(3-chloro-2-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125077(CHEMBL3623001)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50189991(CHEMBL214857 | N-(3-chloro-2-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50189990(CHEMBL215786 | N-(3-chloro-4-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50041611((2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRY...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125077(CHEMBL3623001)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50072963(CHEMBL3410548)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125077(CHEMBL3623001)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Binding affinity to ERalpha receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50084948(CHEMBL195515 | GW7604)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50190003(2-(4-(4-(5-chloro-2-fluorophenylamino)-7-methoxyqu...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50189998(CHEMBL385471 | N-(5-chloro-2-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50189994(CHEMBL276154 | N-(3-chloro-4-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Agonist activity at progesterone receptor in human MCF7 cells in presence of 0.25 uM tamoxifenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50084948(CHEMBL195515 | GW7604)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetProgesterone receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50125081(CHEMBL3622997)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Agonist activity at progesterone receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76FCNPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50189992(CHEMBL385479 | N-(3-chloro-2-fluorophenyl)-7-metho...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DTMPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50371359(CHEMBL403774)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of ebrB2 expressed in human MCF7 cells by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RSHPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50371373(CHEMBL402507)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of ebrB2 expressed in human MCF7 cells by autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RSHPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50371364(CHEMBL428777)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RSHPubMed
Displayed 1 to 50 (of 166 total ) | Next | Last >>
Jump to: