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Found 539 with Last Name = 'poon' and Initial = 'sf'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109106(US8609852, 13)copy SMILEScopy InChI
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109136(US8609852, 43)copy SMILEScopy InChI
Affinity DataKi:  0.650nM ΔG°:  -52.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109101(US8609852, 7)copy SMILEScopy InChI
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109157(US8609852, 64)copy SMILEScopy InChI
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109121(US8609852, 28)copy SMILEScopy InChI
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109102(US8609852, 8)copy SMILEScopy InChI
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109115(US8609852, 117 | US8609852, 34)copy SMILEScopy InChI
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109115(US8609852, 117 | US8609852, 34)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109182(US8609852, 91)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109120(US8609852, 27)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109176(US8609852, 85)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109099(US8609852, 5)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109105(US8609852, 12)copy SMILEScopy InChI
Affinity DataKi:  1.10nM ΔG°:  -51.1kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109100(US8609852, 6)copy SMILEScopy InChI
Affinity DataKi:  1.20nM ΔG°:  -50.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50181753(3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine ...)copy SMILEScopy InChI
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109113(US8609852, 20)copy SMILEScopy InChI
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109114(US8609852, 21)copy SMILEScopy InChI
Affinity DataKi:  1.5nM ΔG°:  -50.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109151(US8609852, 58)copy SMILEScopy InChI
Affinity DataKi:  1.5nM ΔG°:  -50.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109147(US8609852, 54)copy SMILEScopy InChI
Affinity DataKi:  1.5nM ΔG°:  -50.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109153(US8609852, 60)copy SMILEScopy InChI
Affinity DataKi:  1.5nM ΔG°:  -50.4kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109116(US8609852, 23)copy SMILEScopy InChI
Affinity DataKi:  1.60nM ΔG°:  -50.2kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109194(US8609852, 103)copy SMILEScopy InChI
Affinity DataKi:  1.60nM ΔG°:  -50.2kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50154997(3-[3-Fluoro-5-(5-pyridin-2-yl-tetrazol-2-yl)-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M657VPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109166(US8609852, 73)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109145(US8609852, 52)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109139(US8609852, 46)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109137(US8609852, 44)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109119(US8609852, 26)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109096(US8609852, 2)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50154997(3-[3-Fluoro-5-(5-pyridin-2-yl-tetrazol-2-yl)-pheny...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6WXBPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109180(US8609852, 89)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109173(US8609852, 82)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109123(US8609852, 30)copy SMILEScopy InChI
Affinity DataKi:  2.30nM ΔG°:  -49.3kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109117(US8609852, 24)copy SMILEScopy InChI
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109098(US8609852, 4)copy SMILEScopy InChI
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109108(US8609852, 15)copy SMILEScopy InChI
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109097(US8609852, 3)copy SMILEScopy InChI
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109112(US8609852, 19)copy SMILEScopy InChI
Affinity DataKi:  2.80nM ΔG°:  -48.8kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109129(US8609852, 36)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109184(US8609852, 93)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50123009(3-Methyl-5-(2-methyl-thiazol-4-ylethynyl)-pyridine...)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109169(US8609852, 76)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50155000(3-{3-Fluoro-5-[5-(1H-imidazol-2-yl)-tetrazol-2-yl]...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M657VPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50155006(3-{3-Fluoro-5-[5-(1H-imidazol-2-yl)-tetrazol-2-yl]...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M657VPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109110(US8609852, 17)copy SMILEScopy InChI
Affinity DataKi:  3.80nM ΔG°:  -48.1kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109168(US8609852, 75)copy SMILEScopy InChI
Affinity DataKi:  4nM ΔG°:  -47.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109156(US8609852, 63)copy SMILEScopy InChI
Affinity DataKi:  4nM ΔG°:  -47.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109181(US8609852, 90)copy SMILEScopy InChI
Affinity DataKi:  4nM ΔG°:  -47.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109152(US8609852, 59)copy SMILEScopy InChI
Affinity DataKi:  4nM ΔG°:  -47.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM109132(US8609852, 39)copy SMILEScopy InChI
Affinity DataKi:  4nM ΔG°:  -47.9kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M06K3US Patent
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