Compile Data Set for Download or QSAR
Found 19 with Last Name = 'cardoso' and Initial = 'sh'
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50568077(CHEMBL4865195)copy SMILES
Affinity DataKi:  0.5nMAssay Description:Binding affinity to Trypanosoma brucei rhodesainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of human guanine-N7 methyltransferase expressed in Saccharomyces cerevisiae YBS40 (MATa leu2 ade2 trp1 his3 ura3 can1 abd1::hisGp360-ABD1)More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminus hexa-histidine tagged-human guanine-N7 methyltransferase expressed in Escherichia coli using GpppAC4 RNA as substrate incuba...More data for this Ligand-Target Pair
TargetSpike glycoprotein(SARS-CoV)TBA
LigandPNGBDBM50559137(CHEMBL4785828)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of spike protein in SARS-CoV infected in human HeLa cells haboring wild type ACE2 assessed as reduction in virus infectivity preincubated ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2DM8PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50568076(CHEMBL4877896)copy SMILES
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50568076(CHEMBL4877896)copy SMILES
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50568075(CHEMBL4845877)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50568074(CHEMBL4859457)copy SMILES
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50568075(CHEMBL4845877)copy SMILES
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50568076(CHEMBL4877896)copy SMILES
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50049066(2-Hydroxynaphthoquinone | CHEBI:44401 | Lawsone | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50568075(CHEMBL4845877)copy SMILES
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50568074(CHEMBL4859457)copy SMILES
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50384788(LAPACHOL)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50568074(CHEMBL4859457)copy SMILES
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50384788(LAPACHOL)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50049066(2-Hydroxynaphthoquinone | CHEBI:44401 | Lawsone | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183B90PubMed