Compile Data Set for Download or QSAR
Found 29 with Last Name = 'kanno' and Initial = 'si'
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)copy SMILES
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50234486(Melophlin C)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8P98PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)copy SMILES
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)copy SMILES
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant CD45 using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)copy SMILES
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant TCPTP (1 to 317 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant TCPTP (1 to 317 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant CD45 using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256931(CHEMBL1186032)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77DTPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7S23PubMed