Compile Data Set for Download or QSAR
Found 196 with Last Name = 'guru' and Initial = 'sk'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PI:PS as substrate after 2 hrs in presence of [33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PI:PS as substrate after 2 hrs in presence of [33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250824(CHEMBL4101278)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK as substrate after 30 mins in presence of [33P]-gamma-ATP by filter bindi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM384362(US9932327, Compound 33)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:CDK-9/Cyclin T1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 1 mg/ml BSA, 0.1% mercaptoethanol) was assayed against a substrate peptide (YSPTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4ZDWUS Patent
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JF1PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250823(CHEMBL4065940)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of CDK9/cyclin T (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PI:PS as substrate after 2 hrs in presence of [33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kalpha/p85 iSH2 domain (unknown origin) expressed in baculovirus using l-alpha-phosphatidylinositol as substrate after 60 mins by ki...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JF1PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250837(CHEMBL4063017)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250815(CHEMBL4089950)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of CDK1/cyclin A (unknown origin) after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) expressed in baculovirus co-expressing p85 using l-alpha-phosphatidylinositol as substrate after 120 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250825(CHEMBL4074567)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250814(CHEMBL4068858)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250813(CHEMBL4095226)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50371402(MERIOLIN 3)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK9/cyclin T (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250816(CHEMBL4097680)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JF1PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PI:PS as substrate after 2 hrs in presence of [33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kgamma (unknown origin) expressed in baculovirus co-expressing p85 using l-alpha-phosphatidylinositol as substrate after 120 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250812(CHEMBL4067806)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204104(CHEMBL3979323)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PI3Kbeta using PIP2 as substrate preincubated for 20 mins followed by substrate addition measured after 20 mins by ap...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250830(CHEMBL4090021)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250828(CHEMBL4098661)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250820(CHEMBL4077931)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250817(CHEMBL4079646)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50371402(MERIOLIN 3)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM384375(US9932327, Compound 34)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:CDK-9/Cyclin T1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 1 mg/ml BSA, 0.1% mercaptoethanol) was assayed against a substrate peptide (YSPTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4ZDWUS Patent
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50263041(CHEMBL4103469)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK as substrate after 30 mins in presence of [33P]-gamma-ATP by filter bindi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250836(CHEMBL4063190)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50592855(CHEMBL5205415)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JF1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM24226(1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]-astemizole binding to human ERG expressed in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMedDrugBank
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250819(CHEMBL4071557)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM119531(US11547697, Compound 529 | US9682141, 529 | US9682...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK5/cyclin p25 (unknown origin) after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK5/cyclin p35 (unknown origin) after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250827(CHEMBL4071643)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM384362(US9932327, Compound 33)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:CDK-2/cyclin A (5-20 mU diluted in 50 mM Hepes pH 7.5, 1 mM DTT, 0.02% Brij35, 100 mM NaCl) was assayed against Histone H1 in a final volume of 25.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4ZDWUS Patent
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM384357(US9932327, Compound Flavopiridol)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:CDK-9/Cyclin T1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 1 mg/ml BSA, 0.1% mercaptoethanol) was assayed against a substrate peptide (YSPTS...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4ZDWUS Patent
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50250828(CHEMBL4098661)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9/cyclin T (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of full length recombinant C-terminal 6His-tagged human Cdk9/full-length human Cyclin T1 after 60 mins in presence of [33P]-gamma-ATP by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1NC4PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin) expressed in baculovirus after 60 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6TJ6PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-180001, India.

Curated by ChEMBL
LigandPNGBDBM50250815(CHEMBL4089950)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK9/cyclin T (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50250829(CHEMBL4090926)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using histone H1 as substrate after 30 mins in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SDHPubMed
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