Compile Data Set for Download or QSAR
Found 13 with Last Name = 'huber' and Initial = 'sk'
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510628(CHEMBL4464729)copy SMILEScopy InChI
Affinity DataKi:  389nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510627(CHEMBL4587609)copy SMILEScopy InChI
Affinity DataKi:  407nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510629(CHEMBL4539697)copy SMILEScopy InChI
Affinity DataKi:  692nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510627(CHEMBL4587609)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510628(CHEMBL4464729)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50013224(CHEMBL351355 | Pyrrolidin-3-yl-acetic acid | Pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510629(CHEMBL4539697)copy SMILEScopy InChI
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 7.24E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510628(CHEMBL4464729)copy SMILEScopy InChI
Affinity DataIC50: 5.37E+4nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50510630(CHEMBL4586784)copy SMILEScopy InChI
Affinity DataIC50: 6.76E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig Maximilians-Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50426075(CHEMBL473104)copy SMILEScopy InChI
Affinity DataKd:  27nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed