Compile Data Set for Download or QSAR
Found 424 with Last Name = 'sakya' and Initial = 'sm'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31149(3-hydroxyquinolin-2(1H)-one, 3)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50081645(CHEMBL3422237)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM136576(US8865706, 16)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM41536(US8865706, 15)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31156(3-hydroxyquinolin-2(1H)-one, 10)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50081646(CHEMBL3422236)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31172(3-hydroxyquinolin-2(1H)-one, 26)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM148176(US8962616, 22 | US8962616, 4)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM136570(US8865706, 9)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM136583(US8865706, 22)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31161(3-hydroxyquinolin-2(1H)-one, 15)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31152(3-hydroxyquinolin-2(1H)-one, 6)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | 5-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50081642(CHEMBL3422244)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182352(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(difluorome...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182338(2-(5-(4-(furan-2-yl)-3-methylphenyl)-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31150(3-hydroxyquinolin-2(1H)-one, 4)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182347(2-(5-(3-chloro-4-(furan-2-yl)phenyl)-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182339(2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM136574(US8865706, 13)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
PharmaPhase Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50293282(CHEMBL504535 | Imrecoxib)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of LPS-induced COX-2 in peritoneal macrophage of C57BL/J6 mouse assessed as prostaglandin E2 formation preincubated for 1 hr followed by L...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VS9PubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182353(2-(3-(difluoromethyl)-5-(3-methyl-4-(thiazol-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182332(2-(5-(4-(furan-2-yl)phenyl)-3-(trifluoromethyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shenogen Pharma Group

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type BRAF (unknown origin)More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM148173(US8962616, 1)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50176545(3-(difluoromethyl)-5-((2R,6S)-2,6-dimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against COX2 in feline whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ876SPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50176555(3-(difluoromethyl)-5-(3-methylpiperidin-1-yl)-1-(5...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ876SPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182345(2-(5-(3-methyl-4-(oxazol-4-yl)phenyl)-3-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31165(naphthyridinone analog.,19)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31153(3-hydroxyquinolin-2(1H)-one, 7)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM136576(US8865706, 16)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing wild type human APP695 assessed as colorimetric reaction by Whole cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H68PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31157(3-hydroxyquinolin-2(1H)-one, 11)copy SMILEScopy InChI
Affinity DataIC50: 38nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31156(3-hydroxyquinolin-2(1H)-one, 10)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50179600(5-(2-fluorobenzylthio)-1-(5-(methylsulfonyl)pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8KKMPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137438(5-Methanesulfonyl-2-[5-(4-methoxy-phenyl)-3-triflu...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01WPPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137423(2-(4-Chloro-3-difluoromethyl-5-phenyl-pyrazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01WPPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137442(2-[3-Difluoromethyl-5-(3-fluoro-4-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01WPPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182335(2-(5-(3-fluoro-4-(furan-2-yl)phenyl)-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31172(3-hydroxyquinolin-2(1H)-one, 26)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137420(2-[5-(4-Ethoxy-phenyl)-3-trifluoromethyl-pyrazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01WPPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50182351(2-(5-(3-chloro-4-(thiazol-4-yl)phenyl)-3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78PWPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50179631(5-(sec-butylthio)-1-(5-(methylsulfonyl)pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8KKMPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50179598(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(propylthio)-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8KKMPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM41536(US8865706, 15)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing wild type human APP695 assessed as colorimetric reaction by Whole cell assayMore data for this Ligand-Target Pair
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