Compile Data Set for Download or QSAR
Found 142 with Last Name = 'treon' and Initial = 'sp'
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473750(US10844077, Compound I-7)copy SMILEScopy InChI
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473766(US10844077, Compound I-9)copy SMILEScopy InChI
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473764(US10844077, Compound II-2)copy SMILEScopy InChI
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473751(US10844077, Compound I-8)copy SMILEScopy InChI
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473751(US10844077, Compound I-8)copy SMILEScopy InChI
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473750(US10844077, Compound I-7)copy SMILEScopy InChI
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473746(US10844077, Compound I-3)copy SMILEScopy InChI
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473766(US10844077, Compound I-9)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473749(US10844077, Compound I-4)copy SMILEScopy InChI
Affinity DataIC50: 0.590nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473701(US10844077, Compound I-1)copy SMILEScopy InChI
Affinity DataIC50: 0.590nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473746(US10844077, Compound I-3)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473748(US10844077, Compound I-2)copy SMILEScopy InChI
Affinity DataIC50: 0.730nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))TBA
LigandPNGBDBM86632(JNK-IN-7)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibition of wild-type human partial length JNK3 (V28 to Q422 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473763(US10844077, Compound II-1)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473749(US10844077, Compound I-4)copy SMILEScopy InChI
Affinity DataIC50: 1.38nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))TBA
LigandPNGBDBM86632(JNK-IN-7)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473701(US10844077, Compound I-1)copy SMILEScopy InChI
Affinity DataIC50: 1.61nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473748(US10844077, Compound I-2)copy SMILEScopy InChI
Affinity DataIC50: 1.63nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473763(US10844077, Compound II-1)copy SMILEScopy InChI
Affinity DataIC50: 1.64nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473752(US10844077, Compound I-10)copy SMILEScopy InChI
Affinity DataIC50: 1.74nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473747(US10844077, Compound I-6)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473764(US10844077, Compound II-2)copy SMILEScopy InChI
Affinity DataIC50: 1.94nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM86632(JNK-IN-7)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of wild-type human full length JNK2 (M1 to Q382 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473752(US10844077, Compound I-10)copy SMILEScopy InChI
Affinity DataIC50: 2.42nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM163700(N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(triflu...)copy SMILEScopy InChI
Affinity DataIC50: 2.43nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375312(US9908872, Compound (I-9))copy SMILEScopy InChI
Affinity DataIC50: 2.43nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473753(US10844077, Compound I-11)copy SMILEScopy InChI
Affinity DataIC50: 3.99nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473747(US10844077, Compound I-6)copy SMILEScopy InChI
Affinity DataIC50: 4.24nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM437992(US10597387, Compound (I-8))copy SMILEScopy InChI
Affinity DataIC50: 5.33nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375310(US9908872, Compound (I-8))copy SMILEScopy InChI
Affinity DataIC50: 5.33nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473753(US10844077, Compound I-11)copy SMILEScopy InChI
Affinity DataIC50: 5.52nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375276(US10597387, Compound (I-1) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM375276(US10597387, Compound (I-1) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561821(CHEMBL4782804)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50373415(CHEMBL256713)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of wild-type human partial length IRAK1 (R194 to S712 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473758(US10844077, Compound III-5)copy SMILEScopy InChI
Affinity DataIC50: 9.06nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM86632(JNK-IN-7)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of wild-type human partial length IRAK1 (R194 to S712 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetHexokinase-4(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM439303(US10633348, Compound (A-17))copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50373415(CHEMBL256713)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of wild-type human partial length IRAK4 (M1 to S460 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM439316(US10633348, Compound (A-12))copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473756(US10844077, Compound III-3)copy SMILEScopy InChI
Affinity DataIC50: 19.4nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473765(US10844077, Compound II-3)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM375281(US10597387, Compound (I-4) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 22.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375281(US10597387, Compound (I-4) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 22.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM375276(US10597387, Compound (I-1) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 22.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM375276(US10597387, Compound (I-1) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 22.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50561824(CHEMBL4784448)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N01B75PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM163700(N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(triflu...)copy SMILEScopy InChI
Affinity DataIC50: 25.3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM375312(US9908872, Compound (I-9))copy SMILEScopy InChI
Affinity DataIC50: 25.3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM473765(US10844077, Compound II-3)copy SMILEScopy InChI
Affinity DataIC50: 25.3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KJ4US Patent
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