Compile Data Set for Download or QSAR
Found 261 with Last Name = 'choi' and Initial = 'sr'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50154364((6R,10bS)-6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10...)copy SMILEScopy InChI
Affinity DataKi:  0.00900nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)copy SMILEScopy InChI
Affinity DataKi:  0.0130nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228440(5-chloro-2-(2-((dimethylamino)methyl)-4-(2-fluoroe...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50119550(5-Chloro-2-(2-dimethylaminomethyl-phenylsulfanyl)-...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228439(5-bromo-2-(2-((dimethylamino)methyl)-4-(2-fluoroet...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.0970nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50301022((+)-9-fluoropropyl-dihydrotetrabenazine | CHEMBL57...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]-iodovinyl-TBZ from VMAT2 in rat striatal homogenate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289166RPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228444(2-(2-((dimethylamino)methyl)-4-(2-fluoroethoxy)phe...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50154366(CHEMBL183470 | [2-(2-Dimethylaminomethyl-phenoxy)-...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228435(5-bromo-2-(2-((dimethylamino)methyl)-4-(3-fluoropr...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228438(3-(4-(2-amino-4-bromophenylthio)-3-((dimethylamino...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228437(2-(2-((dimethylamino)methyl)-4-(2-fluoroethoxy)phe...)copy SMILEScopy InChI
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50154365(2-(2-((dimethylamino)methyl)phenoxy)-5-iodoaniline...)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)copy SMILEScopy InChI
Affinity DataKi:  0.740nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)copy SMILEScopy InChI
Affinity DataKi:  0.740nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)copy SMILEScopy InChI
Affinity DataKi:  0.870nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)copy SMILEScopy InChI
Affinity DataKi:  0.870nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228436(2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)ph...)copy SMILEScopy InChI
Affinity DataKi:  0.950nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50301021((+)-dihydrotetrabenzaine | CHEMBL576222 | US110532...)copy SMILEScopy InChI
Affinity DataKi:  1.03nMAssay Description:Displacement of [125I]-iodovinyl-TBZ from VMAT2 in rat striatal homogenate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289166RPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50091095(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methoxy...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228443(2-(4-(2-aminophenylthio)-3-((dimethylamino)methyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228441(2-(4-(2-amino-4-fluoro-phenylthio)-3-((dimethylami...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228445(3-(4-(2-aminophenylthio)-3-((dimethylamino)methyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50109052((4-Benzothiazol-2-yl-phenyl)-methyl-amine | 4-(ben...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228433(2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)ph...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8XRRPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50479453(CHEMBL519255)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]IMPY from beta-amyloid plaques in AD patient brainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7CWTPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Binding affinity for Norepinephrine transporter (NET) expressed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481119(AZD-2184 | CHEMBL570378)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481123(CHEMBL570610)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073437(CHEMBL113382 | [5-Chloro-2-(2-dimethylaminomethyl-...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Inhibition of 5-HT reuptake (SERT) in rat brain synaptosomes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485236(BAY-949172 | CHEBI:79033 | FLORBETABEN F18 | Florb...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481133(BAY-94-9172 | CHEMBL566723)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM52401(4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]-N,N-dimet...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485233(AZD-4694 | CHEMBL2042123)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50119549(2-(5-Amino-4-chloro-2-nitro-phenylsulfanyl)-N,N-di...)copy SMILEScopy InChI
Affinity DataKi:  2.39nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481126(CHEMBL566709)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481121(AV-45 | Florbetapir F-18)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FW6PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50484946((18F)AV-45 | 18F-AV-45 | AV-45 F-18 | Amyvid | CHE...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485234(CHEMBL2042124)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485235(CHEMBL2042245)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976FJPubMed
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