Compile Data Set for Download or QSAR
Found 43 with Last Name = 'mahmood' and Initial = 'sr'
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50344942(CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate measured in 25 to 30 mins by time dependent inhibition a...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate measured in 25 to 30 mins by time dependent inhibition a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50344942(CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate measured in 0 to 5 mins by time dependent inhibition ass...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292984(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292981(CHEMBL489094 | N-(4-Fluorophenyl)-1-[(4-([(3S)-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292983(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292979(CHEMBL474130 | N-(3-Fluorophenyl)-1-[3-(4-([(3S)-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292981(CHEMBL489094 | N-(4-Fluorophenyl)-1-[(4-([(3S)-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using 7BQ substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292979(CHEMBL474130 | N-(3-Fluorophenyl)-1-[3-(4-([(3S)-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using 7BQ substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate measured in 0 to 5 mins by time dependent inhibition ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292982(CHEMBL523933 | N-(3-Fluorophenyl)-1-[(4-([(3R)-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292985(3-((1-[(4-([(3S)-3-Methyl-1-piperazinyl]methyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292980(1-[(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292985(3-((1-[(4-([(3S)-3-Methyl-1-piperazinyl]methyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using 7BQ substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292980(1-[(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using 7BQ substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using 7BQ substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292982(CHEMBL523933 | N-(3-Fluorophenyl)-1-[(4-([(3R)-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using 7BQ substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412868(CHEMBL474129)copy SMILEScopy InChI
Affinity DataEC50:  63.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292980(1-[(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methyl)...)copy SMILEScopy InChI
Affinity DataEC50:  39.8nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292981(CHEMBL489094 | N-(4-Fluorophenyl)-1-[(4-([(3S)-3-m...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataEC50:  12.6nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292982(CHEMBL523933 | N-(3-Fluorophenyl)-1-[(4-([(3R)-3-m...)copy SMILEScopy InChI
Affinity DataEC50:  19.9nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292983(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)copy SMILEScopy InChI
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292984(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)copy SMILEScopy InChI
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292985(3-((1-[(4-([(3S)-3-Methyl-1-piperazinyl]methyl)phe...)copy SMILEScopy InChI
Affinity DataEC50:  3.98nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM85389(CAS_52906-92-0 | Motilin)copy SMILEScopy InChI
Affinity DataEC50:  0.0398nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50344942(CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...)copy SMILEScopy InChI
Affinity DataEC50:  50.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50247157((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Agonist activity at human Ghrelin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human Ghrelin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50412867(CHEMBL514475)copy SMILEScopy InChI
Affinity DataEC50:  50.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed
TargetMotilin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50292979(CHEMBL474130 | N-(3-Fluorophenyl)-1-[3-(4-([(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  25.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208666TPubMed