Affinity DataKi: 26.4nMAssay Description:Compound was evaluated for its ability to displace [3H]Ins(1,4,5)P3 from membranes prepared from bovine adrenal corticlesMore data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membraneMore data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 1.15E+4nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (S substrate)More data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (S substrate)More data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 1.65E+4nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (S substrate)More data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 8.14E+4nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (S substrate)More data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 1.44E+5nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (R metabolically resistant)More data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 1.48E+5nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (R metabolically resistant)More data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: 5.35E+5nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (R metabolically resistant)More data for this Ligand-Target Pair
Affinity DataKi: 9.78E+5nMAssay Description:Tested for the ability to inhibit Ins(1,4,5)P 3-phosphataseMore data for this Ligand-Target Pair
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataKi: >1.00E+8nMAssay Description:Tested for inhibition of 5-phosphatase isolated from human erythrocyte membrane (R metabolically resistant)More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 2(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:The compound was tested for inhibitory activity against IInositol 1,4,5-trisphosphate receptor in SH-SY5Y cell lineMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 2(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 26.5nMAssay Description:The compound was tested for inhibitory activity against Inositol 1,4,5-trisphosphate receptor in SH-SY5Y cell lineMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 2(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:The compound was tested for inhibitory activity against Inositol 1,4,5-trisphosphate receptor in SH-SY5Y cell lineMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 2(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:The compound was tested for inhibitory activity against Inositol 1,4,5-trisphosphate receptor in L15 cell lineMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 2(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:The compound was tested for inhibitory activity against Inositol 1,4,5-trisphosphate receptor in SH-SY5Y cell lineMore data for this Ligand-Target Pair
TargetType 1 InsP3 receptor isoform S2(Sus scrofa)
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataIC50: 61nMpH: 7.6Assay Description:Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 7.6 using [3H]Ins(1,4,5)P3 as the radioligand.More data for this Ligand-Target Pair
TargetType 1 InsP3 receptor isoform S2(Sus scrofa)
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataIC50: 78nMpH: 6.8Assay Description:Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 6.8 using [3H]Ins(1,4,5)P3 as the radioligand.More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 2(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:The compound was tested for inhibitory activity against Inositol 1,4,5-trisphosphate receptor in L15 cell lineMore data for this Ligand-Target Pair
TargetType 1 InsP3 receptor isoform S2(Sus scrofa)
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.65E+3nMpH: 7.6Assay Description:Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 7.6 using [3H]Ins(1,4,5)P3 as the radioligand.More data for this Ligand-Target Pair
TargetType 1 InsP3 receptor isoform S2(Sus scrofa)
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Mayo Foundation for Medical Education and Research
Curated by ChEMBL
Affinity DataIC50: 9.11E+3nMpH: 6.8Assay Description:Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 6.8 using [3H]Ins(1,4,5)P3 as the radioligand.More data for this Ligand-Target Pair