Compile Data Set for Download or QSAR
Found 28 with Last Name = 'jabaris' and Initial = 'ss'
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50181089(6-(azepan-1-yl)-N,2-dicyclopropyl-5-methylpyrimidi...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Antagonist activity at muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50245245(4-{2-(3,4-Bis-difluoromethoxy-phenyl)-2-[4-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GST-tagged PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50085135(4-(8-(3-nitrophenyl)-1,7-naphthyridin-6-yl)benzoic...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50119355(2-{4-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GST-tagged PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50108504(4-(8-(benzo[c][1,2,5]oxadiazol-5-yl)-1,7-naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of GST-tagged PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human PDE4B2 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE4B3 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE4D2 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE4D4 in particular fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE4B1 in particular fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE4D1 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMedDrugBank
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human PDE4D4 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human PDE4B1 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human PDE4D5 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human PDE4B3 in particular fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human PDE4D3 in cytosolic fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 166nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMedDrugBank
TargetCytochrome P450 2C9(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50174022((E)-8-(3-(2-(3-methyl-1,2,4-oxadiazol-5-yl)-2-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human PDE4B2 in particular fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 239nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50236083(5-[1-(3-Cyclopentyloxy-4-methoxy-phenyl)-meth-(Z)-...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of human PDE4D3 in particular fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human PDE4D5 in particular fraction of lungMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50236078(5-(3-(cyclopentyloxy)-4-methoxybenzylidene)-2-thio...)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50236078(5-(3-(cyclopentyloxy)-4-methoxybenzylidene)-2-thio...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZNKPubMed