Compile Data Set for Download or QSAR
Found 257 with Last Name = 'appleby' and Initial = 't'
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50230294(CHEMBL4071740)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50230211(CHEMBL4063126)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ137KPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataKi:  6.70nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ137KPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50230212(CHEMBL4084776)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50230213(CHEMBL4092526)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50230210(CHEMBL4090107)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50230209(CHEMBL4100272)copy SMILEScopy InChI
Affinity DataKi:  65nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ137KPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Selcia Ltd.

Curated by ChEMBL
LigandPNGBDBM50230293(CHEMBL4082253)copy SMILEScopy InChI
Affinity DataKi:  795nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CHK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194053(5-4-2,3-difluorophenoxy)phenylamino)-3-hydroxy-N-1...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194048(5-4-3,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-1...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194024(3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-phenoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of MEK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194030(5-4-2,5-dichlorophenoxy)-3-fluorophenylamino)-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194056(5-3-chloro-4-2,3-dichlorophenoxy)phenylamino)-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194039(5-4-2-chloro-3,5-difluorophenoxy)-3-fluorophenylam...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194041(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194061(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-1...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194036(5-3-chloro-4-2-chloro-5-fluorophenoxy)phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194051(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-m...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194024(3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-phenoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194023(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-t...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194031(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-4...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194026(5-4-2,5-dichlorophenoxy)phenylamino)-N-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194045(5-4-2,5-dichlorophenoxy)phenylamino)-N-1,3-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194065(5-4-2-chloro-3,5-difluorophenoxy)phenylamino)-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187848(5-(2,3-dichlorophenylamino)-3-hydroxy-N-(1-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194034(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194046(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-1...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187817(5-(2-chloro-4-iodophenylamino)-3-hydroxy-N-isoprop...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194063(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194016(3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-3-trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194062(3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-phenylthio)p...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194028(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194055(5-4-2,5-dichlorophenoxy)phenylamino)-N-2,3-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research and Development

LigandPNGBDBM26673(6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dih...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4G2VPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194059(5-4-2-chloro-3-trifluoromethyl)phenoxy)-3-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194019(5-4-2,5-dichlorophenoxy)phenylamino)-N-2,3-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194033(5-4-2-chloro-4-fluorophenoxy)-2-methylphenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194050(5-4-benzylphenylamino)-3-hydroxy-N-1-hydroxypropan...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194025(5-4-2,5-dichlorophenoxy)phenylamino)-3-hydroxy-N-2...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194058(5-4-2-fluoro-3-trifluoromethyl)phenoxy)phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194022(5-4-2-fluoro-5-trifluoromethyl)phenoxy)phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187841(3-hydroxy-5-(4-iodo-2-methylphenylamino)-N-isoprop...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194057(5-4-2,4-dichlorophenoxy)phenylamino)-3-hydroxy-N-1...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194064(5-3-chloro-4-2-chloro-3-trifluoromethyl)phenoxy)ph...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194040(5-4-2,3-dichlorophenoxy)phenylamino)-3-hydroxy-N-1...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194021(5-4-2-chloro-5-fluorophenoxy)phenylamino)-3-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194037(5-4-2-chloro-4-fluorophenoxy)phenylamino)-3-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194027(5-3-chloro-4-2-chloro-4-fluorophenoxy)phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194038(5-4-2-chloro-3-trifluoromethyl)phenoxy)phenylamino...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
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