Compile Data Set for Download or QSAR
Found 361 with Last Name = 'fujisawa' and Initial = 't'
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278561( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(propan-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278614((2E)-3-(1-{[3-(2,6- Dichlorophenyl)-5-(3- methoxyo...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278633(US10040791, Example 95)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278569( (2E)-3-(1-{[5-(2-Methoxypropan-2-yl)-3-(2,4,6-tri...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278540( (2E)-3-(3-Methyl-1-{[5-(3-methyloxetan-3-yl)-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278541( (2E)-3-(1-{[5-(3-Methoxyoxetan-3-yl)-3-(2,4,6-tri...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278628((2E)-3-(1-{[5-(1-Aminocyclobutyl)-3-(2,4,6-trichlo...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278542( (2E)-3-(1-{[5-(3-Methoxyoxetan-3-yl)-3-(2,4,6-tri...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278546( (2E)-[1-{[5-(3-Methyloxetan-3-yl)-3-(2,4,6-trichl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278566( (2E)-3-(1-{[3-(2,6-Dichloro-3-fluorophenyl)-5-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278615((2E)-3-(1-{[3-(2,6- Dichlorophenyl)-5-(2- methylox...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278624((2E)-[1-({5-[1- (Methylamino)cyclopropyl]-3- (2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278587((2E)-3-(1-{[3-(2,6-Dichloro-4- fluorophenyl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0JPZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278539((2E)-3-(1-{[5-(3-Methyloxetan-3-yl)-3-(2,4,6-trich...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278595((2E)-3-(1-{[5-(1- Methoxycyclopropyl)-3-(2,4,6- tr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278630(US10040791, Example 92)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278703( (2E)-3-(1-Methyl-3-{[5-(1-methylcyclopropyl)-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278671((2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(dimethylamin...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278565( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(2-methoxypr...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278543( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(3-ethyloxet...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278545( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(2-hydroxypr...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278588((2E)-3-(7-Fluoro-1-{[5-(2- fluoropropan-2-yl)-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278613((2E)-3-(1-{[3-(2,6- Dichlorophenyl)-5-(3- methylox...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278621((2E)-3-(3-Methyl-1-{[5-[1-(methylamino)cyclobutyl]...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278697( (2E)-3-[1-({5-[(5R)7-Acryloyl-5-methyl-4,7-diazas...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278702((2E)-3-(3-[5-tert-Butyl-3-(2,4,6-trichlorophenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278553( (2E)-[1-{[3-(2,4-Dichloro-6-fluorophenyl)-5-(1-me...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278559((2E)-3-(1-{[5-(2-Fluoropropan-2-yl)-3-(2,4,6-trich...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278568( (2E)-3-(1-{[3-(2,6-Dichloro-3-fluorophenyl)-5-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278577( (2E)-3-(1-{[3-(2-Bromo-6-chlorophenyl)-5-(tert-bu...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278631((2E)-3-(1-{[5-(1-Cyanocyclobutyl)-3-(2,4,6-trichlo...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278676( (2E)-3-(1-{[5-(Dimethylamino)-3-(2,4,6-trichlorop...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278549( (2E)-3-(1-{[3-(3,5-Dichloropyridin-2-yl)-5-(2-flu...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278574( (2E)-3-(1-{[5-(2-Fluoropropan-2-yl)-3-(2,4,6-tric...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278575( (2E)-3-(1-{[5-(1-Methylcyclopropyl)-3-(2,4,6-tric...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278583( (2E)-3-(3-Fluoro-1-{[5-(2-fluoropropan-2-yl)-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278585((2E)-3-(1-{[3-(2,4-Dichloro-6- fluorophenyl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278620((2E)-3-(1-{[5-[1- (Dimethylamino)cyclopropyl]- 3-(...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278567( (2E)-3-(1-{[5-(Propan-2-yl)-3-(2,4,6-trichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278604((2E)-3-(3-Chloro-1-{[5-(2- fluoropropan-2-yl)-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278552( (2E)-3-(1-{[3-(2,4-Dichloro-6-fluorophenyl)-5-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278593((2E)-3-(1-{[3-(4-Chloro-2,6- dimethylphenyl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278623((2E)-[1-({5-[2- (Methylamino)propan-2-yl]-3- (2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278673( (2E)-3-(1-{[3-(2,6-Dichlorophenyl)-5-(pyrrolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278594((2E)-3-(1-{[3-(2,6-Dichloro-4- methylphenyl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278554( (2E)-[1-{[3-(2,4-Dichloro-6-fluorophenyl)-5-(2-fl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278589((2E)-3-(1-{[5-(1,1- Difluoroethyl)-3-(2,4,6- trich...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278597((2E)-3-(1-{[3-(2,4-Dichloro-6- methylphenyl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Daiichi Sankyo Company, Limited; National Cancer Center

US Patent
LigandPNGBDBM278601((2E)-3-(1-{[3-(2,4-Dichloro-5- fluorophenyl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SF8US Patent
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