Compile Data Set for Download or QSAR
Found 193 with Last Name = 'gould' and Initial = 't'
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439791(CHEMBL2419706 | US9181266, 5)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439799(CHEMBL2419698 | US9181266, 13)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM247785(US10112931, Example 388 | US9434719, 388 as TFA sa...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetComplement factor D [24-253](Homo sapiens (Human))
Novartis Pharma AG

LigandPNGBDBM171350(1-(2-((1R,3S,5R)-3-((6-Bromopyridin-2-yl)carbamoyl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Briefly, recombinant human or murine FD catalytic domain (10 nM concentration) were incubated with compound at various concentrations for 1 h at room...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146127(US8957068, 162)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458782(CHEMBL4216510)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50279397(CHEMBL4169151 | US11311527, Cpd ID IDH889 | US1137...)copy SMILEScopy InChI
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM247849(US10112931, Example 456 | US9434719, 456 | US96886...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458778(CHEMBL4208648)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetComplement factor D [24-253](Homo sapiens (Human))
Novartis Pharma AG

LigandPNGBDBM171272(1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...)copy SMILEScopy InChI
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:Briefly, recombinant human or murine FD catalytic domain (10 nM concentration) were incubated with compound at various concentrations for 1 h at room...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146127(US8957068, 162)copy SMILEScopy InChI
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In DepthDetails
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439792(CHEMBL2419705 | US9181266, 24)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439796(CHEMBL2419701 | US9181266, 26)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50279397(CHEMBL4169151 | US11311527, Cpd ID IDH889 | US1137...)copy SMILEScopy InChI
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
TargetComplement factor D [24-253](Homo sapiens (Human))
Novartis Pharma AG

LigandPNGBDBM171350(1-(2-((1R,3S,5R)-3-((6-Bromopyridin-2-yl)carbamoyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:Recombinant human FD (10 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in 0.1 M PBS (pH 7.4) ...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458777(CHEMBL4216983)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as NADPH consumption using alpha-ketoglutarate as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM247843(US10112931, Example 450 | US9434719, 450 as TFA sa...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146127(US8957068, 162)copy SMILEScopy InChI
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM247822(US10112931, Example 429 | US9434719, 429 | US96886...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetComplement factor D [24-253](Homo sapiens (Human))
Novartis Pharma AG

LigandPNGBDBM171272(1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Recombinant human FD (10 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in 0.1 M PBS (pH 7.4) ...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM247801(US10112931, Example 404 | US9434719, 404 | US96886...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458781(CHEMBL4214694)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alphaKG as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458784(CHEMBL4216196)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alphaKG as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458777(CHEMBL4216983)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439800(CHEMBL2419697 | US9181266, 1)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458777(CHEMBL4216983)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) assessed as NADPH consumption using alpha-ketoglutarate as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458783(CHEMBL4217038)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) expressed in HCT116 cells assessed as reduction in 2-HG levels after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48CZPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439797(CHEMBL2419700 | US9181266, 22)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439798(CHEMBL2419699 | US9181266, 38)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439794(CHEMBL2419703)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50279397(CHEMBL4169151 | US11311527, Cpd ID IDH889 | US1137...)copy SMILEScopy InChI
Affinity DataIC50: 72nMMore data for this Ligand-Target Pair
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50318567(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50458784(CHEMBL4216196)copy SMILEScopy InChI
Affinity DataIC50: 81nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50615219(CHEMBL5273829)copy SMILES
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146015(US8957068, 50)copy SMILEScopy InChI
Affinity DataIC50: 94nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50615219(CHEMBL5273829)copy SMILES
Affinity DataIC50: 97nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research Incorporated

Curated by ChEMBL
LigandPNGBDBM50318567(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of PARP2 (unknown origin) after 60 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6SZ5PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research Incorporated

Curated by ChEMBL
LigandPNGBDBM50318567(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of PARP2 (unknown origin) assessed as nicotinamide concentration by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50615222(CHEMBL5269195)copy SMILES
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146034(US8957068, 129 | US8957068, 69)copy SMILEScopy InChI
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50615218(CHEMBL5289157)copy SMILES
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439799(CHEMBL2419698 | US9181266, 13)copy SMILEScopy InChI
Affinity DataIC50: 142nMAssay Description:Inhibition of PARP1 (unknown origin) assessed as nicotinamide concentration by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146053(US8957068, 88)copy SMILEScopy InChI
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM145968(US8957068, 3)copy SMILEScopy InChI
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50615218(CHEMBL5289157)copy SMILES
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146015(US8957068, 50)copy SMILEScopy InChI
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50615222(CHEMBL5269195)copy SMILES
Affinity DataIC50: 170nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146064(US8957068, 99)copy SMILEScopy InChI
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM146208(US8957068, 260)copy SMILEScopy InChI
Affinity DataIC50: 190nMMore data for this Ligand-Target Pair
In DepthDetails
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