Compile Data Set for Download or QSAR
Found 312 with Last Name = 'grebe' and Initial = 't'
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300953(N-(4-((6S,8R)-7-(2,2-difluoropropyl)-8-methyl-6,7,...)copy SMILES
Affinity DataIC50: 0.0398nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300962(1-(3-fluoropropyl)-N-(3-methoxy-4-((6S,8R)-8-methy...)copy SMILES
Affinity DataIC50: 0.0631nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300955(N-(4-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8...)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300969(BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...)copy SMILES
Affinity DataIC50: 0.126nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha expression in presence of cycloheximide by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299111(US10125135, Example 1)copy SMILES
Affinity DataIC50: 0.126nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299117((6S,8R)-7-((l-fluorocyclopropyl)methyl)-6-(4-(2-(3...)copy SMILES
Affinity DataIC50: 0.126nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548427(CHEMBL4780809)copy SMILES
Affinity DataIC50: 0.126nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548432(CHEMBL4785486)copy SMILES
Affinity DataIC50: 0.158nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300969(BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...)copy SMILES
Affinity DataIC50: 0.158nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha expression by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299115((6S,8R)-7-(2-fluoro-2-methylpropyl)-6-(4-(2-(3-(fl...)copy SMILES
Affinity DataIC50: 0.158nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299139((6R,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...)copy SMILES
Affinity DataIC50: 0.158nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300969(BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...)copy SMILES
Affinity DataIC50: 0.158nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300994(2,2-difluoro-3- ((6S,8R)-6-(4- ((1-(3- fluoropropy...)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299144((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300998(N-(4-((6S,8R)- 7-(2-fluoro-2- methylpropyl)- 8-met...)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300968(N-(1-(3- fluoropropyl) azetidin-3-yl)- N-methyl-6-...)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299124((6S,8R)-6-(4-(2- (3-(fluoromethyl) azetidin-1- yl)...)copy SMILES
Affinity DataIC50: 0.251nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300959(6-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8,9-...)copy SMILES
Affinity DataIC50: 0.316nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300997(6-((6S,8R)-7- (2-fluoro-2- methylpropyl)- 8-methyl...)copy SMILES
Affinity DataIC50: 0.316nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548435(CHEMBL4792890)copy SMILES
Affinity DataIC50: 0.316nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300930(N-(4-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-me...)copy SMILES
Affinity DataIC50: 0.316nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM301004(6-((6S,8R)-7- (2,2- difluoropropyl)- 8-methyl- 6,7...)copy SMILES
Affinity DataIC50: 0.316nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548428(CHEMBL4779715)copy SMILES
Affinity DataIC50: 0.398nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548433(CHEMBL4782483)copy SMILES
Affinity DataIC50: 0.398nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299151((6S,8R)-6-(5-(2- (3-(fluoromethyl) azetidin-1- yl)...)copy SMILES
Affinity DataIC50: 0.398nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300931((6S,8R)-7-((1-fluorocyclopropyl)methyl)-6-(4-((1-(...)copy SMILES
Affinity DataIC50: 0.398nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299119((6S,8R)-7-((l-fluorocyclopropyl)methyl)-6-(5-(2-(3...)copy SMILES
Affinity DataIC50: 0.398nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299120((6S,8R)-6-(4-(2-(3-(fluoromethyl)azetidin-1-yl)eth...)copy SMILES
Affinity DataIC50: 0.501nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300950(2,2-difluoro-3-((6S,8R)-6-(5-((1-(3-fluoropropyl)a...)copy SMILES
Affinity DataIC50: 0.501nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM301006((S)-6-(8,8- dimethyl-7- (2,2,2- trifluoroethyl)- 6...)copy SMILES
Affinity DataIC50: 0.501nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299162((6S,8R)-7-(2,2-difluoroethyl)-6-(5-(2-(3-(fluorome...)copy SMILES
Affinity DataIC50: 0.501nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548431(CHEMBL4744329)copy SMILES
Affinity DataIC50: 0.631nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300924(6-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methy...)copy SMILES
Affinity DataIC50: 0.631nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548429(CHEMBL4797178)copy SMILES
Affinity DataIC50: 0.794nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM301007((S)-6-(7-(2,2- difluoroethyl)- 8,8-dimethyl- 6,7,8...)copy SMILES
Affinity DataIC50: 0.794nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299144((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...)copy SMILES
Affinity DataIC50: 0.794nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548434(CHEMBL4779640)copy SMILES
Affinity DataIC50: 1nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299111(US10125135, Example 1)copy SMILES
Affinity DataIC50: 1nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300978(6-((6S,8R)-7- (2,2- difluoroethyl)- 6,8-dimethyl- ...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ER-alpha level incubated for 18 to 24 hrs by Alexa fluor 488/Hoechst sta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548433(CHEMBL4782483)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299119((6S,8R)-7-((l-fluorocyclopropyl)methyl)-6-(5-(2-(3...)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548428(CHEMBL4779715)copy SMILES
Affinity DataIC50: 2nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300968(N-(1-(3- fluoropropyl) azetidin-3-yl)- N-methyl-6-...)copy SMILES
Affinity DataIC50: 2nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300955(N-(4-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8...)copy SMILES
Affinity DataIC50: 2nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299139((6R,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...)copy SMILES
Affinity DataIC50: 2nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300969(BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM299162((6S,8R)-7-(2,2-difluoroethyl)-6-(5-(2-(3-(fluorome...)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50548427(CHEMBL4780809)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM300953(N-(4-((6S,8R)-7-(2,2-difluoropropyl)-8-methyl-6,7,...)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Displacement of fluormone ES2 green reagent from human GST-tagged ERalpha LBD (282 to 595 residues) expressed in baculovirus infected insect cells in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GDBPubMed
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM568474(US11420984, Example 24)copy SMILES
Affinity DataIC50: 3nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q243GVUS Patent
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