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Found 217 with Last Name = 'hirano' and Initial = 't'
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)copy SMILEScopy InChI
Affinity DataKi:  0.590nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)copy SMILEScopy InChI
Affinity DataKi:  0.780nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)copy SMILEScopy InChI
Affinity DataKi:  0.950nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)copy SMILEScopy InChI
Affinity DataKi:  1.33nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1a receptor(RAT)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35667(AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...)copy SMILEScopy InChI
Affinity DataKi:  1.45nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50017721(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959KGVPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50097224(1-Methyl-4-thioxanthen-9-ylidene-piperidine | 1-me...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959KGVPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataKi:  6.36nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50097222(4-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959KGVPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataKi:  9.42nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataKi:  9.42nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)copy SMILEScopy InChI
Affinity DataKi:  12.3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1a receptor(RAT)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM50029644(CHEMBL296908 | N-(3-(4-(4-(2-oxo-3,4-dihydroquinol...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Binding affinity of the compound towards Vasopressin V1a receptor in rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Tokyo Medical and Dental University (TMDU)

Curated by ChEMBL
LigandPNGBDBM50097215(4-Fluoren-9-ylidene-1-methyl-piperidine | CHEMBL34...)copy SMILEScopy InChI
Affinity DataKi:  199nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959KGVPubMed
TargetVasopressin V1a receptor(RAT)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)copy SMILEScopy InChI
Affinity DataKi:  325nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1a receptor(RAT)
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataKi:  524nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35723(CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QGCPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM50029644(CHEMBL296908 | N-(3-(4-(4-(2-oxo-3,4-dihydroquinol...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity of the compound towards Vasopressin V1a receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
RIKEN

Curated by ChEMBL
LigandPNGBDBM50017721(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ac-KRSK-MCA peptide/SAM as substrate preincubated fo...More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:Concentration of the compound which inhibit [3H]-AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094079((4-Amino-2-methyl-phenyl)-(7-chloro-2,3,4,5-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094068((2-Chloro-4-ethylamino-phenyl)-(7-chloro-2,3,4,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094086((4-Allylamino-2-chloro-phenyl)-(2,3,4,5-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094082((2-Chloro-4-pyrrol-1-yl-phenyl)-(2,3,4,5-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094066((2-Chloro-4-pyrazol-1-yl-phenyl)-(2,3,4,5-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094075((2-Chloro-4-pyrrolidin-1-yl-phenyl)-(2,3,4,5-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094075((2-Chloro-4-pyrrolidin-1-yl-phenyl)-(2,3,4,5-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Binding affinity of the compound against human Vasopressin V2 receptor expressed in HeLa cells was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QRKPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094070(CHEMBL136109 | [2-Chloro-4-(3-methyl-pyrazol-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094074((2-Chloro-4-dimethylamino-phenyl)-(7-chloro-2,3,4,...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094072((2-Chloro-4-pyrrolidin-1-yl-phenyl)-(7-chloro-2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094089((2-Chloro-4-propylamino-phenyl)-(2,3,4,5-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094067((2-Chloro-4-dimethylamino-phenyl)-(2,3,4,5-tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094077((2-Chloro-4-diethylamino-phenyl)-(2,3,4,5-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094078((4-Butylamino-2-chloro-phenyl)-(2,3,4,5-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198670(CHEMBL3960590)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SRMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198661(CHEMBL3955849)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SRMPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094087((2-Chloro-4-pentylamino-phenyl)-(2,3,4,5-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198660(CHEMBL3928231)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SRMPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094069((2-Chloro-4-ethylamino-phenyl)-(2,3,4,5-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094083((2-Chloro-4-methylamino-phenyl)-(2,3,4,5-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198677(CHEMBL3929427)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SRMPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Second Tokushima Institute of New Drug Research

Curated by PDSP Ki Database
LigandPNGBDBM50094076(CHEMBL434654 | N-[4-(7-Chloro-2,3,4,5-tetrahydro-b...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Binding affinity of the compound towards rat Vasopressin V2 receptor after peroral administration of the compoundMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50094088(CHEMBL136790 | [2-Chloro-4-(3-methyl-pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of [3H]-AVP binding to human Vasopressin V2 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1R04PubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198662(CHEMBL3966957)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SRMPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355243(CHEMBL1835836)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VJ6PubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198682(CHEMBL3918835)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SRMPubMed
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