Compile Data Set for Download or QSAR
Found 164 with Last Name = 'keenan' and Initial = 't'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132351(({4-[6-(2,6-Dichloro-phenyl)-8-(3-dimethylamino-pr...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21J995TPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | 3-(2-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HRQPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM13930((2S)-N-tert-butyl-1-[(2R)-2-[(8S,11S)-8-(carbamoyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2SNQPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM902((3R)-oxolan-3-yl N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2SNQPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132348(({4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-di...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21J995TPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01V7PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132322(({2-[(2-{4-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290235NPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132554((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132550((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-propionyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132541((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMedMMDB
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132541((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMedMMDB
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Pennsylvania

LigandPNGBDBM13931((2S)-N-[(2S,3R)-4-{[(8S,11S)-8-[(2R)-butan-2-yl]-7...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2SNQPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132558((E)-(12S,13R,14S,17R,21S,23S,24R,25R,27R)-17-Ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132542((S)-1-[(S)-2-(3,4,5-Trimethoxy-phenyl)-butyryl]-pi...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM3071(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 38 | 2-ani...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21J995TPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50221656(CHEMBL3706663)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290235NPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM81618(2,6,9-Trisubstitute purine, 3)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HRQPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132560((S)-1-((S)-2-Benzo[1,3]dioxol-5-yl-butyryl)-piperi...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM81619(2,6,9-Trisubstitute purine, 4)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HRQPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM81620(2,6,9-Trisubstitute purine, 5)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HRQPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132324(3-{4-Amino-7-[4-(2-hydroxy-ethyl)-phenyl]-7H-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290235NPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132544((S)-1-((S)-2-Phenyl-butyryl)-piperidine-2-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132544((S)-1-((S)-2-Phenyl-butyryl)-piperidine-2-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132339(3-[4-Amino-7-(4-{2-[(2-hydroxy-ethyl)-methyl-amino...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290235NPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50451556(CHEMBL3084838)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Src-mediated dentine resorption in rabbit-osteoclast assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01V7PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132334(CHEMBL104215 | [(2-{4-[4-Amino-5-(3-hydroxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290235NPubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
ARIAD Gene Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50132551(1-(1-Ethyl-propylcarbamoyl)-piperidine-2-carboxyli...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7G0SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM81623(2,6,9-Trisubstitute purine, 9 (AP23451))copy SMILEScopy InChI
Affinity DataIC50: 67nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HRQPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Mus musculus (Mouse))
ARIAD Pharmaceuticals, Inc.

LigandPNGBDBM50318870(((4-(2-(cis-4-aminocyclohexyl)-9-ethyl-9H-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:2,6,9-Trisubstituted purines were evaluated for their src kinase inhibitory activities using an ELISA assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3QTQPubMedMMDB
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HRQPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Mus musculus (Mouse))
ARIAD Pharmaceuticals, Inc.

LigandPNGBDBM81725(2,6,9-Trisubstituted Purine, AP23517)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:2,6,9-Trisubstituted purines were evaluated for their src kinase inhibitory activities using an ELISA assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3QTQPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50132352(({3-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-di...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21J995TPubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372187(US10239882, Example 38)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372213(US10239882, Example 84)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372212(US10239882, Example 83)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372211(US10239882, Example 82)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372210(US10239882, Example 81)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372209(US10239882, Example 80)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372208(US10239882, Example 79)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372207(US10239882, Example 78)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372206(US10239882, Example 76)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372205(US10239882, Example 74)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372204(US10239882, Example 72)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372203(US10239882, Example 67)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372202(US10239882, Example 66)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372201(US10239882, Example 62)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372174(US10239882, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372175(US10239882, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM372176(US10239882, Example 17)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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BindingDB Entry DOI: 10.7270/Q24J0HFDUS Patent
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