TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at human CRTH2 transfected in human KB8 cells assessed as inhibition of PGD2-induced increase in intracellular Ca2+ by fluo-4AM d...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at human CRTH2 transfected in human KB8 cells assessed as inhibition of PGD2-induced increase in intracellular Ca2+ by fluo-4AM d...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair