TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 0.497nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Tokyo Medical and Dental University (TMDU)
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical and Dental University
Curated by ChEMBL
Tokyo Medical and Dental University
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
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