Compile Data Set for Download or QSAR
Found 191 with Last Name = 'kubota' and Initial = 't'
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50012950(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50012950(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346122(2-(4-(2-(4-bromo-5-methylthiophen-2-yl)-5-ethyl-6-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetLanosterol synthase(Homo sapiens (Human))
National Institute of Advanced Industrial Science and Technology (AIST)

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetCathepsin D(Bos taurus)
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Tested for inhibition of Cathepsin D from bovineMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMedMMDB
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022525(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346121(2-(4-(2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346123(2-(4-(5-ethyl-2-(5-fluorothiophen-2-yl)-6-methylpy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetLanosterol synthase(Homo sapiens (Human))
National Institute of Advanced Industrial Science and Technology (AIST)

Curated by ChEMBL
LigandPNGBDBM50456340(CHEMBL4207987)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3HN7PubMed
TargetPepsin A(Porcine)
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Tested for inhibition of pepsin from porcineMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMedMMDB
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346120(2-(4-(2-(5-bromothiophen-2-yl)-5-ethyl-6-methylpyr...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022530(3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022530(3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346119(2-(4-(5-ethyl-6-methyl-2-(5-(methylthio)thiophen-2...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346100(4-(5-allyl-6-ethyl-2-phenylpyrimidin-4-ylamino)ben...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022525(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022530(3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022527(3-Hydroxy-4-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022527(3-Hydroxy-4-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346104(4-(5-allyl-6-methyl-2-(thiophen-3-yl)pyrimidin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346112(4-(5-allyl-2-(5-methoxythiophen-2-yl)-6-methylpyri...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346100(4-(5-allyl-6-ethyl-2-phenylpyrimidin-4-ylamino)ben...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50012952(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346103(4-(5-allyl-6-methyl-2-(thiophen-2-yl)pyrimidin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346096(4-(5-cyano-6-methyl-2-phenylpyrimidin-4-ylamino)be...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetLanosterol synthase(Homo sapiens (Human))
National Institute of Advanced Industrial Science and Technology (AIST)

Curated by ChEMBL
LigandPNGBDBM50456341(CHEMBL4212932)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3HN7PubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022524(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022524(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346091(4-(5-ethyl-6-methyl-2-phenylpyrimidin-4-ylamino)be...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GDBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346111(4-(5-allyl-6-methyl-2-(5-methylthiophen-2-yl)pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346089(4-(5-allyl-6-methyl-2-phenylpyrimidin-4-ylamino)be...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346118(2-(4-(5-allyl-2-(5-methoxythiophen-2-yl)-6-methylp...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346109(4-(5-allyl-6-methyl-2-m-tolylpyrimidin-4-ylamino)b...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))TBA
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)copy SMILEScopy InChI
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N27FKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346108(4-(5-allyl-6-methyl-2-p-tolylpyrimidin-4-ylamino)b...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346110(4-(5-allyl-2-(4-methoxyphenyl)-6-methylpyrimidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110NQPubMed
TargetLanosterol synthase(Homo sapiens (Human))
National Institute of Advanced Industrial Science and Technology (AIST)

Curated by ChEMBL
LigandPNGBDBM50456342(CHEMBL4210513)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3HN7PubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50012952(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XJZPubMed
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