Compile Data Set for Download or QSAR
Found 306 with Last Name = 'marquardt' and Initial = 't'
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM228279(US9555022, Example 02.17)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM228278(US9555022, Example 02.16)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM228270(US9555022, Example 02.09)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542581(CHEMBL4642174)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM258444(US9512130, 2)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of MPS1 in human HeLa cells assessed as reduction in spindle assembly checkpoint incubated for 4 hrs by p-histone H3/Hoechst 33342 stainin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312960(3-[1-(2,3-Difluoro-4-methylbenzyl)-5-fluoro-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542592(CHEMBL4645348)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM259464(US9512126, 1)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MPS1 in human HeLa cells assessed as reduction in spindle assembly checkpoint incubated for 4 hrs by p-histone H3/Hoechst 33342 stainin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542591(CHEMBL4640247)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MPS1 in human HeLa cells assessed as reduction in spindle assembly checkpoint incubated for 4 hrs by p-histone H3/Hoechst 33342 stainin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM259464(US9512126, 1)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542583(CHEMBL4634949)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542581(CHEMBL4642174)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM329340((2R)—N-{4-[2-({4-[(3-fluoroazetidin-1-yl)carb...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254841(US9487554, 28)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542592(CHEMBL4645348)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542591(CHEMBL4640247)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50512456(CHEMBL4469414)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM259482(US9512126, 23)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312961(3-[1-(2,3-Difluoro-4-methylbenzyl)-6-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM258444(US9512130, 2)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254826(US9487554, 13)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM259482(US9512126, 23)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542591(CHEMBL4640247)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542559(CHEMBL4635693)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50512459(CHEMBL4581793)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542558(CHEMBL4646772)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM228273(US9555022, Example 02.11)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM228261(US9555022, Example 02.01)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM258444(US9512130, 2)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM329342((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(2-o...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254825(US9487554, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50512456(CHEMBL4469414)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254815(US9487554, 2)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM259464(US9512126, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542583(CHEMBL4634949)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254814(US9487554, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254815(US9487554, 2)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542562(CHEMBL4632648)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM258453(US9512169, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24B3081US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542561(CHEMBL4638962)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312944(3-[5-Fluoro-1-(2-fluoro-4-methylbenzyl)-6-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM228316(US9555022, Example 02.44)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254825(US9487554, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM329334((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(met...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254824(US9487554, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254826(US9487554, 13)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254814(US9487554, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetAldo-keto reductase family 1 member C3/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM254836(US9487554, 23)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMpH: 7.0Assay Description:Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK99Q9US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312945(3-[1-(2-Fluoro-4-methylbenzyl)-6-methyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50542579(CHEMBL4649817)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56VPPubMed
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