Compile Data Set for Download or QSAR
Found 442 with Last Name = 'mizukami' and Initial = 't'
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)copy SMILEScopy InChI
Affinity DataKi:  340nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)copy SMILEScopy InChI
Affinity DataKi:  580nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444908(CHEMBL3099624)copy SMILEScopy InChI
Affinity DataKi:  670nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444908(CHEMBL3099624)copy SMILEScopy InChI
Affinity DataKi:  870nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444888(CHEMBL3099621)copy SMILEScopy InChI
Affinity DataKi:  1.02E+3nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444888(CHEMBL3099621)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Noncompetitive inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogeni...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of PGPH activity of human 26S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50399672(CHEMBL2178342)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B3QPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50399673(CHEMBL2178343)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B3QPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50432548(LACTACYSTIN)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50399674(CHEMBL2178344)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B3QPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50324535(3-{[9-(Dimethylamino)nonanoyl](hydroxy)amino}propa...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of KDM2A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB475VPubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458013(CHEMBL4215864)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444899(CHEMBL3099640)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B3QPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458009(CHEMBL4205518)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151585(CHEMBL3774476)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3P22PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444904(CHEMBL3099622)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151584(CHEMBL3775613)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3P22PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50121213(CHEMBL3622371)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TWVPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B3QPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151583(CHEMBL3774920)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3P22PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458008(CHEMBL4204198)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444889(CHEMBL3099620)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50399675(CHEMBL2178345)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of HDAC8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B3QPubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444907(CHEMBL3099623)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444888(CHEMBL3099621)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444908(CHEMBL3099624)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458009(CHEMBL4205518)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50140044(CHEMBL3764353)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TWVPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50131110(CHEMBL437226 | Cyclic peptide analogue)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of Farnesyltransferase by Scintillation Proximity AssayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9B5JPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151587(CHEMBL3774486)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3P22PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50140043(CHEMBL3765529)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TWVPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444908(CHEMBL3099624)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50140045(CHEMBL3764836)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TWVPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50151588(CHEMBL3775735)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3P22PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444906(CHEMBL3099636)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444906(CHEMBL3099636)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444908(CHEMBL3099624)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444901(CHEMBL3099638)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444901(CHEMBL3099638)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222W81PubMed
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