Compile Data Set for Download or QSAR
Found 89 with Last Name = 'pirali' and Initial = 't'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human LXF-289 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514759(CHEMBL4571131)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132093(US8841288, CL27e)copy SMILEScopy InChI
Affinity DataIC50: 20nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human MCF7 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HepG2 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50030792(CHEMBL3342401)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human MCF7 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514752(CHEMBL4458549)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50461837(CHEMBL4226608)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Antagonist activity at TRPV1 (unknown origin) expressed in human SH-SY5Y cells assessed as inhibition of capsaicin-induced calcium increase after 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0JSMPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514752(CHEMBL4458549)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132092(US8841288, CL12)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132097(US8841288, CL 64a)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132096(US8841288, CL55b)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132095(US8841288, CL55a)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514752(CHEMBL4458549)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human MCF7 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514752(CHEMBL4458549)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514757(CHEMBL4466117)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132098(US8841288, CL 129A)copy SMILEScopy InChI
Affinity DataIC50: 140nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human DAN-G cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50454819(CHEMBL4208781)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
LigandPNGBDBM50549365(CHEMBL3403742)copy SMILES
Affinity DataIC50: 228nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6PPZPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132091(US8841288, CL5)copy SMILEScopy InChI
Affinity DataIC50: 260nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132089(US8841288, TP714)copy SMILEScopy InChI
Affinity DataIC50: 260nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetShort transient receptor potential channel 1(Homo sapiens)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50450630(CHEMBL101896)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3Q2GPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132094(US8841288, CL29a)copy SMILEScopy InChI
Affinity DataIC50: 320nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514762(CHEMBL4531545)copy SMILEScopy InChI
Affinity DataIC50: 327nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50454818(CHEMBL4206526)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
LigandPNGBDBM50549358(CHEMBL4753023)copy SMILES
Affinity DataIC50: 361nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6PPZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514761(CHEMBL4472707)copy SMILEScopy InChI
Affinity DataIC50: 407nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514754(CHEMBL4588288)copy SMILEScopy InChI
Affinity DataIC50: 413nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50454816(CHEMBL4210198)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514758(CHEMBL4451614)copy SMILEScopy InChI
Affinity DataIC50: 477nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Universita degli Studi del Piemonte Orientale A. Avogadro

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HDAC in human SHSY5Y cells by fluorimetric cellular activity assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 1(Homo sapiens)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50450629(CHEMBL4177187)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3Q2GPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50454821(CHEMBL4209779)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
LigandPNGBDBM50450626(CHEMBL4162723)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3Q2GPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)copy SMILEScopy InChI
Affinity DataIC50: 605nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human DAN-G cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50454820(CHEMBL4214662)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514755(CHEMBL4443904)copy SMILEScopy InChI
Affinity DataIC50: 636nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50454815(CHEMBL4218468)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50454814(CHEMBL4214873)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MZDPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro”

US Patent
LigandPNGBDBM132090(US8841288, CL1)copy SMILEScopy InChI
Affinity DataIC50: 730nMT: 2°CAssay Description:Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4H5XUS Patent
Displayed 1 to 50 (of 89 total ) | Next | Last >>
Jump to: