Compile Data Set for Download or QSAR
Found 79 with Last Name = 'rehm' and Initial = 't'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
GC University

LigandPNGBDBM11023((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetCholinesterase(Homo sapiens (Human))
GC University

LigandPNGBDBM11023((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 850nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529816(CHEMBL4529234)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529816(CHEMBL4529234)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529814(CHEMBL4563379)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529814(CHEMBL4563379)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529815(CHEMBL4543139)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529815(CHEMBL4543139)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
GC University

LigandPNGBDBM173580(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529813(CHEMBL4447489)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529813(CHEMBL4447489)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529811(CHEMBL4436753)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529811(CHEMBL4436753)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529810(CHEMBL4466760)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529810(CHEMBL4466760)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529817(CHEMBL4559911)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529817(CHEMBL4559911)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529818(CHEMBL4461598)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529812(CHEMBL4534332)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529818(CHEMBL4461598)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50529812(CHEMBL4534332)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ93W9PubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
GC University

LigandPNGBDBM173576(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 2.56E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
GC University

LigandPNGBDBM173575(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 2.68E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
GC University

LigandPNGBDBM173577(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 2.88E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
GC University

LigandPNGBDBM173581(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+4nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
GC University

LigandPNGBDBM173574(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 3.22E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
GC University

LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetCholinesterase(Homo sapiens (Human))
GC University

LigandPNGBDBM173574(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetCholinesterase(Homo sapiens (Human))
GC University

LigandPNGBDBM173580(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 4.48E+4nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31274(Chalcone derivative, B)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
GC University

LigandPNGBDBM173574(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.02E+4nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetCholinesterase(Homo sapiens (Human))
GC University

LigandPNGBDBM173581(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+5nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31275(Chalcone derivative, B-1)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
GC University

LigandPNGBDBM173578(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMpH: 6.8Assay Description:The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31273(Chalcone derivative, A)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31281(Chalcone derivative, H)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31279(Chalcone derivative, F)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31276(Chalcone derivative, C)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31277(Chalcone derivative, D)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31278(Chalcone derivative, E)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31280(Chalcone derivative, G)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMpH: 7.4 T: 2°CAssay Description:Interference of the p53-MDM2 binding by test compounds was measured in a 96-well polypropylene round-bottom microtiter plate (Costar, Serocluster). H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetCholinesterase(Homo sapiens (Human))
GC University

LigandPNGBDBM173577(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetCholinesterase(Homo sapiens (Human))
GC University

LigandPNGBDBM173579(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetCholinesterase(Homo sapiens (Human))
GC University

LigandPNGBDBM173582(N,N',N''-((2,2',2''-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
GC University

LigandPNGBDBM173579(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
GC University

LigandPNGBDBM173579(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMpH: 6.8Assay Description:The α-glucosidase inhibition activity was performed with slight modifications according to method. Total volume of 100 無 reaction mixture conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
GC University

LigandPNGBDBM173577(N',N'',N'''-(pyridine-2,4,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMpH: 7.7Assay Description:The AChE inhibition assay was performed according to the Ellman's method. Total volume of 100 無 reaction mixture contained 60 無 50 mM Na2HPO4 b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H7TPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31273(Chalcone derivative, A)copy SMILEScopy InChI
Affinity DataKd:  2.20E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31274(Chalcone derivative, B)copy SMILEScopy InChI
Affinity DataKd:  9.00E+4nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Max Planck Institute

LigandPNGBDBM31276(Chalcone derivative, C)copy SMILEScopy InChI
Affinity DataKd:  2.44E+5nMpH: 7.4 T: 2°CAssay Description:NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W3KPubMed
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