Found 35 with Last Name = 'soares da costa' and Initial = 't' TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 30nM ΔG°: -44.7kJ/mole IC50: 203nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Inhibition of Escherichia coli recombinant BPL using 3H-biotin as substrate after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 90nM ΔG°: -41.8kJ/mole IC50: 530nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 90nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Inhibition of human recombinant BPL using 3H-biotin as substrate after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 225nM ΔG°: -39.5kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: 420nM ΔG°: -37.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 660nM ΔG°: -36.7kJ/mole IC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 1.17E+3nM ΔG°: -35.2kJ/mole IC50: 7.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 1.17E+3nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 1.17E+3nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 1.83E+3nM ΔG°: -34.1kJ/mole IC50: 1.16E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.85E+3nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.43E+3nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/mole IC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >1.00E+4nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]-biotin from human BPL after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
