BindingDB PrimarySearch_ki

Found 342 with Last Name = 'svensson' and Initial = 't'

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239559(CHEMBL4073594)copy SMILEScopy InChI

IC50: 0.398nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239550(CHEMBL4060741)copy SMILEScopy InChI

IC50: 0.398nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239549(CHEMBL4096646)copy SMILEScopy InChI

IC50: 0.501nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239552(CHEMBL4070433)copy SMILEScopy InChI

IC50: 0.501nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239540(CHEMBL4086230)copy SMILEScopy InChI

IC50: 0.501nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239542(CHEMBL4069417)copy SMILEScopy InChI

IC50: 0.501nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234161(CHEMBL4091680)copy SMILEScopy InChI

IC50: 0.600nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234157(CHEMBL4089227)copy SMILEScopy InChI

IC50: 0.600nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239545(CHEMBL4092688)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239560(CHEMBL4081062)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of photolabeling of 24 kDa polypeptide in adenosine A1 receptorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239551(CHEMBL4091365)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234161(CHEMBL4091680)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239553(CHEMBL4083582)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234157(CHEMBL4089227)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239548(CHEMBL4080523)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239557(CHEMBL4102634)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239555(CHEMBL4094000)copy SMILEScopy InChI

IC50: 0.631nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234169(CHEMBL4101902)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239556(CHEMBL4083733)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239547(CHEMBL4104746)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239559(CHEMBL4073594)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234158(CHEMBL4072500)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of PI3K subunit p110gamma assessed as formation of phosphatidylinositide-3-phosphate product formation after 30 mins by fluorescence polar...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234169(CHEMBL4101902)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239561(CHEMBL4061810)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239546(CHEMBL4065004)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239539(CHEMBL4088952)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239543(CHEMBL4101730)copy SMILEScopy InChI

IC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234158(CHEMBL4072500)copy SMILEScopy InChI

IC50: 0.800nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239561(CHEMBL4061810)copy SMILEScopy InChI

IC50: 1nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239558(CHEMBL4078365)copy SMILEScopy InChI

IC50: 1.30nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239550(CHEMBL4060741)copy SMILEScopy InChI

IC50: 1.30nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239543(CHEMBL4101730)copy SMILEScopy InChI

IC50: 1.30nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239541(CHEMBL4064748)copy SMILEScopy InChI

IC50: 1.30nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239555(CHEMBL4094000)copy SMILEScopy InChI

IC50: 1.30nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239547(CHEMBL4104746)copy SMILEScopy InChI

IC50: 1.60nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239560(CHEMBL4081062)copy SMILEScopy InChI

IC50: 1.60nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239554(CHEMBL4073335)copy SMILEScopy InChI

IC50: 1.60nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239544(CHEMBL4099101)copy SMILEScopy InChI

IC50: 1.60nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239542(CHEMBL4069417)copy SMILEScopy InChI

IC50: 1.60nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239556(CHEMBL4083733)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234159(CHEMBL4099419)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239540(CHEMBL4086230)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of photolabeling of 24 kDa polypeptide in adenosine A1 receptorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234154(CHEMBL4100327)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239553(CHEMBL4083582)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239548(CHEMBL4080523)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239539(CHEMBL4088952)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239549(CHEMBL4096646)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234150(CHEMBL4061634)copy SMILEScopy InChI

IC50: 3.16nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50234150(CHEMBL4061634)copy SMILEScopy InChI

IC50: 3.20nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2TF00MMPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

PNG

BDBM50239557(CHEMBL4102634)copy SMILEScopy InChI

IC50: 3.20nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 cells assessed as reduction in Akt phosphorylation at Ser473 residue preincubated for 60 mins followed by Anti...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2T43W8XPubMed

Displayed 1 to 50 (of 342 total ) | Next | Last >>

Targets 16 ▿
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform 61
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform 53
- Metabotropic glutamate receptor 5 45
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 43
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 41
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 28
- Potassium voltage-gated channel subfamily A member 5 27
- Carboxypeptidase B2 27
- Carboxypeptidase N catalytic chain 9
- Metabotropic glutamate receptor 1 2
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1
- 5-hydroxytryptamine receptor 1A 1
- Casein kinase I isoform gamma-3 1
- Endothelin-converting enzyme 1 1
- Potassium voltage-gated channel subfamily H member 2 1
- ...
Publications 6 ▿
- Bioorg Med Chem Lett 27: 679-687 (2017) 140
- J Med Chem 60: 5057-5071 (2017) 91
- Bioorg Med Chem 22: 2261-8 (2014) 36
- Bioorg Med Chem Lett 16: 4792-5 (2006) 28
- Bioorg Med Chem Lett 24: 1269-73 (2014) 28
- Bioorg Med Chem Lett 16: 4788-91 (2006) 19
Institutions 3 ▿
- [AstraZeneca] 295
- [AstraZeneca R&D M£lndal] 28
- [AstraZeneca R&D Mölndal] 19
Affinity: 0.40 to 1.0E+6 nM▿
- IC50 342
- Affinity ≤ nM
Xtal structures: 10
Docked structures: 0
Catalog Cmpds: 5