Compile Data Set for Download or QSAR
Found 47 with Last Name = 'taguchi' and Initial = 't'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataKi:  3.62nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 3 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50279772(2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...)copy SMILEScopy InChI
Affinity DataKi:  3.72nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50279772(2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...)copy SMILEScopy InChI
Affinity DataKi:  4.11nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 3 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataKi:  22.5nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)copy SMILEScopy InChI
Affinity DataKi:  23.4nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataKi:  41.7nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 3 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataKi:  47.7nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)copy SMILEScopy InChI
Affinity DataKi:  53.5nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 3 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataKi:  65.9nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 3 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50376408(CHEMBL409928)copy SMILEScopy InChI
Affinity DataIC50: 3.49nMAssay Description:Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1SMMPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50376406(CHEMBL259435)copy SMILEScopy InChI
Affinity DataIC50: 4.45nMAssay Description:Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1SMMPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50376406(CHEMBL259435)copy SMILEScopy InChI
Affinity DataIC50: 4.45nMAssay Description:Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1SMMPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50376407(CHEMBL410126)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1SMMPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  29.4nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094845((+/-)-2-Amino-6-fluoro-4-hydroxy-bicyclo[3.1.0]hex...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  2.64E+3nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50:  0.570nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50279772(2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)copy SMILEScopy InChI
Affinity DataEC50:  18.3nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094848((1S,2S,3R,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hex...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094846((1S,2R,3R,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hex...)copy SMILEScopy InChI
Affinity DataEC50:  4.49E+3nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50:  0.570nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  34.2nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  16.6nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)copy SMILEScopy InChI
Affinity DataEC50:  62.8nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50:  2.07nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  29.4nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094848((1S,2S,3R,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hex...)copy SMILEScopy InChI
Affinity DataEC50:  1.71E+4nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50:  94.7nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  16.6nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094847((+/-)-2-Amino-3,3-difluoro-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50:  3.62E+4nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094847((+/-)-2-Amino-3,3-difluoro-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094846((1S,2R,3R,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hex...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094843((+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 3 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  45.4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094845((+/-)-2-Amino-6-fluoro-4-hydroxy-bicyclo[3.1.0]hex...)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094841((+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 3 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094844((+/-)-2-Amino-6-methyl-bicyclo[3.1.0]hexane-2,6-di...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formatio...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094844((+/-)-2-Amino-6-methyl-bicyclo[3.1.0]hexane-2,6-di...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50279772(2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...)copy SMILEScopy InChI
Affinity DataEC50:  50.3nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2
expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50:  80.9nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50094842((+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dica...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 3 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DC8PubMed